Annals ofAntibiotics

Volume: 6 - Number: 49 - February 15, 2008

Outstanding

Lack of Pharmacokinetic Interaction between Linezolid and Antacid in Healthy Volunteers

In Vitro Activity of Moxifloxacin against 923 Anaerobes Isolated from Human Intra-Abdominal Infections

Induction and Inhibition of Ciprofloxacin Resistance-Conferring Mutations in Hypermutator Bacteria

In Vivo Efficacies and Pharmacokinetics of DX-619, a Novel Des-Fluoro(6) Quinolone, against Streptococcus pneumoniae in a Mouse Lung Infection Model

Clinical therapeutics

Multiple-Dose Pharmacokinetics and Safety of the New Antifungal Triazole BAL4815 after Intravenous Infusion and Oral Administration of Its Prodrug, BAL8557, in Healthy Volunteers

Experimental Therapeutics

In Vitro and In Vivo Interactions between Miltefosine and Other Antileishmanial Drugs

In Vivo and In Vitro Studies of Antibiotic Release from and Bacterial Growth Inhibition by Antibiotic-Impregnated Polymethylmethacrylate Hip Spacers

In Vivo Efficacies and Pharmacokinetics of DX-619, a Novel Des-Fluoro(6) Quinolone, against Streptococcus pneumoniae in a Mouse Lung Infection Model

Lovastatin Has Significant Activity against Zygomycetes and Interacts Synergistically with Voriconazole

Microdialysis Study of Imipenem Distribution in the Intraperitoneal Fluid of Rats with or without Experimental Peritonitis

Multiple Combination Bactericidal Testing of Staphylococcal Biofilms from Implant-Associated Infections

Mechanisms of Action

Lethal Action of Quinolones against a Temperature-Sensitive dnaB Replication Mutant of Escherichia coli

Pharmacology

Lack of Pharmacokinetic Interaction between Linezolid and Antacid in Healthy Volunteers

Resistence mechanism

In Vitro Effects of Thiazolides on Giardia lamblia WB Clone C6 Cultured Axenically and in Coculture with Caco2 Cells

Induction and Inhibition of Ciprofloxacin Resistance-Conferring Mutations in Hypermutator Bacteria

Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Telithromycin Transport

Molecular Genetic and Structural Modeling Studies of Staphylococcus aureus RNA Polymerase and the Fitness of Rifampin Resistance Genotypes in Relation to Clinical Prevalence

Multidrug-Resistant Pseudomonas aeruginosa: Risk Factors and Clinical Impact

Susceptibility

High Prevalence of Antimicrobial Resistance among Shigella Isolates in the United States Tested by the National Antimicrobial Resistance Monitoring System from 1999 to 2002

In Vitro Activity of Fosfomycin against Extended-Spectrum-ß-Lactamase- Producing Escherichia coli and Klebsiella pneumoniae: Comparison of Susceptibility Testing Procedures

In Vitro Activity of Moxifloxacin against 923 Anaerobes Isolated from Human Intra-Abdominal Infections

Multicenter Antimicrobial Susceptibility Survey of Gram-Negative Bacteria Isolated from Patients with Community-Acquired Infections in the People\'s Republic of China