Arthritis and infection
Investigation of infectious agents associated with arthritis by reverse transcription PCR of bacterial rRNA
Autoantigen
Giantin is the major Golgi autoantigen in human anti-Golgi complex sera
Autoimmune arthritis
CD4+CD25+ immunoregulatory T cells may not be involved in controlling autoimmune arthritis
Chondrocyte and fibroblasts synovial
The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes
Experimental Arthritis
Susceptibility to collagen-induced arthritis is modulated by TGF? responsiveness of T cells
Inhibition of established collagen-induced arthritis with a tumour necrosis factor-? inhibitor expressed from a self-contained doxycycline regulated plasmid
Induction of IL-10-producing CD4+CD25+ T cells in animal model of collagen-induced arthritis by oral administration of type II collagen
Enhanced osteoclast development in collagen-induced arthritis in interferon-? receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis
Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis
Collagen-induced arthritis is exacerbated in IL-10-deficient mice
The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis
The relationship between predicted peptide–MHC class II affinity and T-cell activation in a HLA-DR?1*0401 transgenic mouse model
Exposure to receptor-activator of NF?B ligand renders pre-osteoclasts resistant to IFN-? by inducing terminal differentiation
Autologous chondrocyte implantation for cartilage repair: monitoring its success by magnetic resonance imaging and histology
Differential recovery of glycosaminoglycan after IL-1-induced degradation of bovine articular cartilage depends on degree of degradation
Osteoarthritis
Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis
Rheumatoid Arthritis
IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-?B- and PI3-kinase/Akt-dependent pathways
Serum levels of cartilage oligomeric matrix protein are elevated in rheumatoid arthritis, but not in inflammatory rheumatic diseases such as psoriatic arthritis, reactive arthritis, Raynaud's syndrome, scleroderma, systemic lupus erythematosus, vasculitis
Increased AP-1 and NF-?B activation and recruitment with the combination of the proinflammatory cytokines IL-1?, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes
Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis
A novel mechanism for the regulation of IFN-? inducible protein-10 expression in rheumatoid arthritis
Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis
Decreased effector memory CD45RA+ CD62L- CD8+ T cells and increased central memory CD45RA- CD62L+ CD8+ T cells in peripheral blood of rheumatoid arthritis patients
Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept
Gene expression induced by interleukin-17 in fibroblast-like synoviocytes of patients with rheumatoid arthritis: upregulation of hyaluronan-binding protein TSG-6
Upregulated hypoxia inducible factor-1? and -2? pathway in rheumatoid arthritis and osteoarthritis
Hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble IL-6 receptor and higher insulin-like growth factor 2
The expansion of CD4+CD28- T cells in patients with rheumatoid arthritis
Systemic Lupus Erythematosus
Decreased levels of soluble amyloid ?-protein precursor and ?-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus
The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus
Wagener`s granulomatosis
Heterogeneity of CD4 and CD8+ memory T cells in localized and generalized Wegener`s granulomatosis
