Annals ofRheumatoid Arthritis

Volume: 2 - Number: 16 - October 15, 2004

Outstanding

Patients with systemic lupus erythematosus have abnormally elevated Epstein–Barr virus load in blood

Measurement of global functional performance in patients with rheumatoid arthritis using rheumatology function tests

The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes

Treatment with recombinant interferon-Betta? reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis

Research article

Patients with systemic lupus erythematosus have abnormally elevated Epstein–Barr virus load in blood

A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis

Nifedipine decreases sVCAM-1 concentrations and oxidative stress in systemic sclerosis but does not affect the concentrations of vascular endothelial growth factor or its soluble receptor 2

Measurement of global functional performance in patients with rheumatoid arthritis using rheumatology function tests

Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross-sectional study

Membrane-associated prostaglandin E synthase-1 is upregulated by proinflammatory cytokines in chondrocytes from patients with osteoarthritis

Autoantibody profile in systemic lupus erythematosus with psychiatric manifestations: a role for anti-endothelial-cell antibodies

Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression

Strong inhibition of TNF-? production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor

The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes

Increased AP-1 and NF-?B activation and recruitment with the combination of the proinflammatory cytokines IL-1?, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes

Association of a specific haplotype across the genes MMP1 and MMP3 with radiographic joint destruction in rheumatoid arthritis

Relationship between radiographic grading of osteoarthritis and the biochemical markers for arthritis in knee osteoarthritis

Enhanced osteoclast development in collagen-induced arthritis in interferon-? receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis

Cortisol and hypothalamic–pituitary–gonadal axis hormones in follicular-phase women with fibromyalgia and chronic fatigue syndrome and effect of depressive symptoms on these hormones

Treatment with recombinant interferon-Betta? reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis

Equipoise, design bias, and randomized controlled trials: the elusive ethics of new drug development

Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice

Autoantibody profile in rheumatoid arthritis during long-term infliximab treatment

CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan–polysaccharide complexes of Gram-positive bacterial cell walls

Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study

Inhibition of established collagen-induced arthritis with a tumour necrosis factor-? inhibitor expressed from a self-contained doxycycline regulated plasmid

Susceptibility to collagen-induced arthritis is modulated by TGF? responsiveness of T cells

Decreased levels of soluble amyloid ?-protein precursor and ?-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus

Role of anti-cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection-associated polyarticular involvement