Annals ofRheumatoid Arthritis

Volume: 3 - Number: 22 - April 15, 2005

Outstanding

The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation

Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score

Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis

The science of rheumatoid arthritis: a prelude

Investigational Article

The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation

Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score

Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes

A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat

Chondrocytes, synoviocytes and dermal fibroblasts all express PH-20, a hyaluronidase active at neutral pH

The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration

Dynamic magnetic resonance of the wrist in psoriatic arthritis reveals imaging patterns similar to those of rheumatoid arthritis

The active metabolite of leflunomide, A77 1726, interferes with dendritic cell function

The determinants of change in tibial plateau bone area in osteoarthritic knees: a cohort study

Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports

Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis

Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]

CD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritis

Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1

Synovial histopathology of psoriatic arthritis, both oligo- and polyarticular, resembles spondyloarthropathy more than it does rheumatoid arthritis

Proliferation and differentiation potential of chondrocytes from osteoarthritic patients

Quantitative ultrasound can assess the regeneration process of tissue-engineered cartilage using a complex between adherent bone marrow cells and a three-dimensional scaffold

Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes

The mechanism of low-concentration sodium nitroprusside-mediated protection of chondrocyte death

ANKH variants associated with ankylosing spondylitis: gender differences

Review

The evolving clinical profile of abatacept (CTLA4–Ig): a novel co-stimulatory modulator for the treatment of rheumatoid arthritis

Modulating co-stimulation: a rational strategy in the treatment of rheumatoid arthritis?

Supplement preface

The science of rheumatoid arthritis: a prelude