An experimental drug, LX211 (LUVENIQ™; oral voclosporin), may become the first approved oral treatment capable of modifying the course of uveitis, a group of serious eye conditions inevitably ...

Radiation from sunlight may be associated with the development of certain autoimmune diseases, particularly in women, according to a study by researchers at the National Institute of Environmental ...

Just over 50 years ago, the late David Jones1 identified (using the periodic acid–Schiff and methenamine silver stains) the unique glomerular pathologic features of membranous nephropathy, thus ...

Purpose of review: Epigenetics encompasses multiple mechanisms by which DNA transcription is altered in various tissues and at different times without changing the underlying gene sequence. ...

Scleroderma (systemic sclerosis) is a complex disease in which extensive fibrosis, vascular alterations, and autoantibodies against various cellular antigens are among the principal features (Figure ...

Objectives. We examined the prevalence of LAC, aCL antibodies (Abs), anti-β2-glycoprotein I (anti-β2GPI) Abs and anti-phosphatidylserine–prothrombin complex (anti-PS/PT) Abs in patients ...

The MerTK receptor tyrosine kinase is an important negative regulator of dendritic cell function and is required to prevent B cell autoimmunity in vivo. It is not currently known however, if any ...

Statins exert a number of anti-inflammatory and immunomodulatory effects in vitro. However, the immunomodulatory effects in vivo are less clarified. In the present study, we investigated whether ...