Annals ofBiology

Volume: 2 - Number: 8 - June 15, 2002

Outstanding

HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism

Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function

regulation of TNF alfa-induced eotaxin release from cultured human airway smooth muscle cells by ß2-agonists and corticosteroids

The heat shock paradox kB-NF does determine cell fate?

Articles

Inhibition of NFkappa-B and AP-1 activation by R- and S-flurbiprofen

HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism

Ceramide binds to the CaLB domain of cytosolic phospholipase A2 and facilitates its membrane docking and arachidonic acid release

Basic Investigation

Thiazolidinediones (PPAR agonists-gamma) but not PPAR alfa agonists increase IRS-2 game expression in 3T3-L1 and human adipocytes

Lens epithelial cells derived fron B-crystallin knockout mice demonstrate hyperproliferation and genomic instability

Specificity, diversity, and convergence in VEGF and TNF alfasignaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells

Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function

Extracellular ATP formation on vascular endothelial cells is mediated by ecto-nucleotide kinase activities via phospho transfer reactions

regulation of TNF alfa-induced eotaxin release from cultured human airway smooth muscle cells by ß2-agonists and corticosteroids

Hiphotesis

The heat shock paradox kB-NF does determine cell fate?

Summary

Neural network model of gene expression

A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology

Upstream binding factor up-regulated in hepatocellular carcinoma is related to the survival and cisplatin-sensitivity of cancer cells

A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor

Hsp27 regulates podocyte cytoskeletal changes in an in vitro model of podocyte process retraction

Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF- B and AP-1 activation and enhances myocardial damage

Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells

Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element

Sodium calcium exchanger plays a key role in alteration of cardiac function in response to pressure overload

Cleavage denatured natural collagen type II by neutrophil gelatinase B reveals enzyme specificity, post-translational modifications in the substrate, and the formation of remnant epitopes in rheumatoid arthritis

Disease-associated mutations in KCNE potassium channel subunits (MiRPs) reveal promiscuous disruption of multiple currents and conservation of mechanism