Annals ofBiology

Volume: 7 - Number: 61 - March 15, 2007

Outstanding

Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

SOCS-1 regulates IL-15–driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential

Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve

Macroautophagy—a novel ß-amyloid peptide-generating pathway activated in Alzheimer\'s disease

Commentaries

Fat meets the cholinergic antiinflammatory pathway

Definitive reports

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

Notch signaling is an important regulator of type 2 immunity

Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells

From the JCB

Macroautophagy—a novel ß-amyloid peptide-generating pathway activated in Alzheimer\'s disease

In This Number

FoxP3 gets a new gig

New target for T regs

NK cells get helpful

NKT cells reject islets

TIM-2 soaks up ferritin

Original Articles

Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing

IL-18–induced CD83+CCR7+ NK helper cells

Lysophosphatidic acid inhibits cholera toxin-induced secretory diarrhea through CFTR-dependent protein interactions

SOCS-1 regulates IL-15–driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential

The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis

The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis

TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis

Tumor cells convert immature myeloid dendritic cells into TGF-ß–secreting cells inducing CD4+CD25+ regulatory T cell proliferation