Annals ofBiology

Volume: 7 - Number: 66 - August 15, 2007

Outstanding

Systemic antithrombotic effects of ADAMTS13

Mesenteric lymph nodes at the center of immune anatomy

Lulling septic shock to sleep

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

Articles

Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens

Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine

Lineage specification and plasticity in CD19– early B cell precursors

Loss of the proapoptotic protein, Bim, breaks B cell anergy

Natural killer cell behavior in lymph nodes revealed by static and real-time imaging

Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function

Structure and binding kinetics of three different human CD1d–-galactosylceramide–specific T cell receptors

Systemic antithrombotic effects of ADAMTS13

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

The primary defect in experimental ileitis originates from a nonhematopoietic source

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE

Brief definitive reports

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

Commentaries

Mesenteric lymph nodes at the center of immune anatomy

From the JCB

Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling

In This Number

Lulling septic shock to sleep

T reg cells get specific

Unhurried NK cells