Annals ofBiology

Volume: 10 - Number: 95 - January 14, 2010

Outstanding

Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo

Discriminating gene expression profiles of memory B cell subpopulations

Tolerance of NK cells encountering their viral ligand during development

Immune-driven recombination and loss of control after HIV superinfection

Articles

Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo

Discriminating gene expression profiles of memory B cell subpopulations

Tolerance of NK cells encountering their viral ligand during development

Continuous engagement of a self-specific activation receptor induces NK cell tolerance

Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma

Avidity maturation of memory CD8 T cells is limited by self-antigen expression

novel pathogenic pathway of immune activation detectable before clinical onset in Huntington\'s disease

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens

Autoregulation of Th1-mediated inflammation by twist2

Human interleukin 17–producing cells originate from a CD161+CD4+ T cell precursor

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

Brief definitive reports

EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN- and IL-2

Immune-driven recombination and loss of control after HIV superinfection

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

Transcriptional role of p53 in interferon-mediated antiviral immunity

From the JEM

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNF

TWEAKing death

Membrane heterogeneities in the formation of B cell receptor–Lyn kinase microclusters and the immune synapse