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Articles

Successful Reversal of Streptozotocin-Induced Diabetes With Stable Allogeneic Islet Function in a Preclinical Model of Type 1 Diabetes

Genetics Reports

Polymorphism Screening of Four Genes Encoding Advanced Glycation End-Product Putative Receptors: Association Study With Nephropathy in Type 1 Diabetic Patients

No Evidence for Linkage or for Diabetes-Associated Mutations in the Activin Type 2B Receptor Gene (ACVR2B) in French Patients With Mature-Onset Diabetes of the Young or Type 2 Diabetes

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Immunology and Transplantation

Pancreatic Biopsy as a Procedure for Detecting In Situ Autoimmune Phenomena in Type 1 Diabetes: Close Correlation Between Serological Markers and Histological Evidence of Cellular Autoimmunity

Peptide and Major Histocompatibility Complex–Specific Breaking of Humoral Tolerance to Native Insulin With the B9-23 Peptide in Diabetes-Prone and Normal Mice

Islet Cell Investigation

Evidence That Extrapancreatic GLUT2-Dependent Glucose Sensors Control Glucagon Secretion

High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program

Increased Uncoupling Protein-2 Levels in ß-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion: Mechanism of Action

A Neuronal Isoform of Nitric Oxide Synthase Expressed in Pancreatic ß-Cells Controls Insulin Secretion

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Metabolism and Signals Transduction

A Daily Rhythm in Glucose Tolerance: A Role for the Suprachiasmatic Nucleus

Protein Kinase C (PKC)- Activation Inhibits PKC- and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells

Hexokinase Isozyme Distribution in Human Skeletal Muscle

Stimulating Effects of Low-Dose Fructose on Insulin-Stimulated Hepatic Glycogen Synthesis in Humans

Noticias del día

Physiopathology

GLUT4 Is Reduced in Slow Muscle Fibers of Type 2 Diabetic Patients: Is Insulin Resistance in Type 2 Diabetes a Slow, Type 1 Fiber Disease?

Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Normalizes Combined Dyslipidemia in Obese Hyperinsulinemic Hamsters

Protein Metabolism in Clinically Stable Adult Cystic Fibrosis Patients With Abnormal Glucose Tolerance

Decreased Susceptibility to Fatty Acid–Induced Peripheral Tissue Insulin Resistance in Women

Assessment of Hepatic Insulin Action in Obese Type 2 Diabetic Patients

Resistance to Exercise-Induced Increase in Glucose Uptake During Hyperinsulinemia in Insulin-Resistant Skeletal Muscle of Patients With Type 1 Diabetes

The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and Induces Insulin Resistance

Increased Fatty Acid Uptake and Altered Fatty Acid Metabolism in Insulin-Resistant Muscle of Obese Zucker Rats

The HIV Protease Inhibitor Indinavir Decreases Insulin- and Contraction-Stimulated Glucose Transport in Skeletal Muscle

The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism

IGF-1 Overexpression Inhibits the Development of Diabetic Cardiomyopathy and Angiotensin II–Mediated Oxidative Stress

The HIV Protease Inhibitor Nelfinavir Induces Insulin Resistance and Increases Basal Lipolysis in 3T3-L1 Adipocytes

Transgenic Overexpression of Leptin Rescues Insulin Resistance and Diabetes in a Mouse Model of Lipoatrophic Diabetes

Insulin Sensitivity of Suppression of Endogenous Glucose Production Is the Single Most Important Determinant of Glucose Tolerance

The Antihyperglycemic Drug -Lipoic Acid Stimulates Glucose Uptake via Both GLUT4 Translocation and GLUT4 Activation: Potential Role of p38 Mitogen-Activated Protein Kinase in GLUT4 Activation

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