Annals ofDiabetes

Volume: 5 - Number: 42 - September 15, 2005

Outstanding

Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Peptides From Common Viral and Bacterial Pathogens Can Efficiently Activate Diabetogenic T-Cells

Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model: A Microarray Overview

Long-Term Islet Graft Survival in NOD Mice by Abrogation of Recurrent Autoimmunity

Complication's

Studies of Rat and Human Retinas Predict a Role for the Polyol Pathway in Human Diabetic Retinopathy

Immunology and Transplantation

Normalization of Multiple Hemostatic Abnormalities in Uremic Type 1 Diabetic Patients After Kidney-Pancreas Transplantation

Assessment of Cytotoxic Lymphocyte Gene Expression in the Peripheral Blood of Human Islet Allograft Recipients: Elevation Precedes Clinical Evidence of Rejection

Mitochondrial Catalase Overexpression Protects Insulin-Producing Cells Against Toxicity of Reactive Oxygen Species and Proinflammatory Cytokines

Peptides From Common Viral and Bacterial Pathogens Can Efficiently Activate Diabetogenic T-Cells

Islet Study

Progression to Islet Destruction in a Cyclophosphamide-Induced Transgenic Model: A Microarray Overview

Dissecting the Role of Glucocorticoids on Pancreas Development

Identification and Cloning of a ß-Cell–Specific Zinc Transporter, ZnT-8, Localized Into Insulin Secretory Granules

Long-Term Islet Graft Survival in NOD Mice by Abrogation of Recurrent Autoimmunity

Glucokinase Is an Integral Component of the Insulin Granules in Glucose-Responsive Insulin Secretory Cells and Does Not Translocate During Glucose Stimulation

Metabolism

Cholesterol Metabolism in Type 1 Diabetes

Transcortical Direct Current Potential Shift Reflects Immediate Signaling of Systemic Insulin to the Human Brain

Expression of Adiponectin Receptor mRNA in Human Skeletal Muscle Cells Is Related to In Vivo Parameters of Glucose and Lipid Metabolism

New Methodology and Database

An Adenovirus Vector for Efficient RNA Interference–Mediated Suppression of Target Genes in Insulinoma Cells and Pancreatic Islets of Langerhans

Obesity Study

Increased Serum Leptin Protects From Adiposity Despite the Increased Glucose Uptake in White Adipose Tissue in Mice Lacking p85 Phosphoinositide 3-Kinase

Involvement of Hypothalamic Histamine H1 Receptor in the Regulation of Feeding Rhythm and Obesity

Physiopathology

Glucose Intolerance in a Large Cohort of Mediterranean Women With Polycystic Ovary Syndrome: Phenotype and Associated Factors

Signal transduction

Induced Adiposity and Adipocyte Hypertrophy in Mice Lacking the AMP-Activated Protein Kinase-2 Subunit

Suppressor of Cytokine Signaling 3 Expression and Insulin Resistance in Skeletal Muscle of Obese and Type 2 Diabetic Patients

Syntaxin 4 Transgenic Mice Exhibit Enhanced Insulin-Mediated Glucose Uptake in Skeletal Muscle