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- NEUROLOGY: -METABOLIC SYNDROME: -Metabolic syndrome and resistance to IV thrombolysis in middle cerebral artery ischemic stroke
Objective: The metabolic syndrome (MetS) is a cluster of vascular risk factors associated with a prothrombotic state. We aimed to evaluate the impact of MetS on the response to systemic tPA ...
- NEUROLOGY: -Site of the ischemic penumbra as a predictor of potential for recovery of functions
Background and Purpose: Diffusion–perfusion mismatch has been used to estimate salvageable tissue and predict potential for recovery in acute stroke. Location of the salvageable tissue may be as ...
- NEUROLOGY: -KCNQ2 and KCNQ3 mutations contribute to different idiopathic epilepsy syndromes
Objective: To explore the involvement of M-type potassium channels KCNQ2, Q3, and Q5 in the pathogenesis of common idiopathic epilepsies. Methods: Sequence analysis of the KCNQ2, Q3, and Q5 coding ...
- NEUROLOGY: -Phenomenology of prolonged febrile seizures
Background: Febrile status epilepticus (FSE) has been associated with hippocampal injury and subsequent mesial temporal sclerosis and temporal lobe epilepsy. However, little is known about the ...
- NEUROLOGY: -Multiple sclerosis and cannabis
Background: A significant minority of patients with multiple sclerosis (MS) use cannabis, yet no study has examined the possible effects on mentation. Here, we report the emotional and cognitive ...
- NEUROLOGY: -Cardiorespiratory fitness and brain atrophy in early Alzheimer disease
Objective: To examine the correlation of cardiorespiratory fitness with brain atrophy and cognition in early-stage Alzheimer disease (AD). Background: In normal aging physical fitness appears to ...
- HYPERTENSION PLUS METABOLIC SYNDROME IS POOR PROGNOSIS: -CVD risk management for hypertensive Asians emphasized
Researchers from Singapore have highlighted the importance of assessing risk factors for cardiovascular disease (CVD) in Asian patients with hypertension. Current Western guidelines recommend that ...
- CEREBROVASCULAR DISEASES: -Right-to-left shunt does not increase white matter damage
Neurology 2008; 71: 101-107 Right-to-left shunt, which is common in patients who have migraine with aura, does not explain their high load of white matter damage, show Italian study results. ...
- NEUROLOGY: -Decreased serum endoglin level in patients with amyotrophic lateral sclerosis: a preliminary report
Abstract & Objectives. Angiogenic mechanisms may have a role to play in the neurodegeneration observed in amyotrophic lateral sclerosis (ALS). The aim of the present study was to measure ...
- CEREBROVASCULAR DEMENTIA & HYPERTENSION: -Antihypertensive treatment in the very elderly may reduce dementia risk
Results from a substudy of the Hypertension in the Very Elderly Trial (HYVET), the HYVET-cognitive function assessment (HYVET-COG), suggest that lowering blood pressure in individuals aged 80 and ...
- BRAIN DEVELOPMENT: - Researchers reveal types of genes necessary for brain development
Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development. ...
- CEREBROVASCULAR DISEASE: - Nonaspirin NSAIDs, cyclooxygenase 2 inhibitors, and the risk for stroke
Background and Purpose There is limited information regarding the cerebrovascular safety of cyclooxygenase 2 inhibitors (coxibs) and noncoxib nonsteroidal antiinflammatory drugs (NSAIDs). We ...
- STROKE UNIT CARE: Not all stroke units are the same
Background and Purpose Very early mobilization may be one of the most important factors contributing to the favorable outcome observed from a stroke unit in Trondheim, Norway. The aims of this study ...
- CEREBROVASCULAR DISEASE: - Nascent aneurysm formation at the basilar terminus induced by hemodynamics
Background and Purpose Hemodynamic insults at arterial bifurcations are hypothesized to play a key role in intracranial aneurysm formation. This study investigates aneurysm-initiating vascular ...
- ISQUEMIA CEREBRAL: - Nogo-A expression after focal ischemic stroke in the adult rat
Background and Purpose The Nogo-A protein is an important inhibitor of axonal remodeling after central nervous system injuries, including ischemic stroke. Interfering with the function of Nogo-A via ...
