Absortion, Distribution, Metabolism and Excretion
Nonsteroidal Anti-Inflammatory Drugs Efficiently Reduce the Transport and Cytotoxicity of Adefovir Mediated by the Human Renal Organic Anion Transporter 1
Hepatic Disposition of the Acyl Glucuronide 1-O-Gemfibrozil-beta-D-glucuronide: Effects of Clofibric Acid, Acetaminophen, and Acetaminophen Glucuronide
Limited Distribution of New Quinolone Antibacterial Agents into Brain Caused by Multiple Efflux Transporters at the Blood-Brain Barrier
Novel Method of Greatly Enhanced Delivery of Liposomes to Lymph Nodes
Secretory Mechanisms of Grepafloxacin and Levofloxacin in the Human Intestinal Cell Line Caco-2
Cardiovascular
Wortmannin, a Potent Antineutrophil Agent, Exerts Cardioprotective Effects in Myocardial Ischemia/Reperfusion
Nonpeptide Factor Xa Inhibitors II. Antithrombotic Evaluation in a Rabbit Model of Electrically Induced Carotid Artery Thrombosis
Vascular Contraction and Relaxation to Thrombin and Trypsin: Thrombomodulin Preferentially Attenuates Thrombin-Induced Contraction
Mibefradil Block of Cloned T-Type Calcium Channels
Cellular y Molecular
Preglomerular Microcirculation Expresses the cAMP-Adenosine Pathway
Polychlorinated Biphenyl-Stimulation of Ca2+ Oscillations in Developing Neocortical Cells: A Role for Excitatory Transmitters and L-Type Voltage-Sensitive Ca2+ Channels
Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
Gz Can Mediate the Acute Actions of µ- and kappa-Opioids but Is Not Involved in Opioid-Induced Adenylyl Cyclase Supersensitization
Modifications in the Phosphoinositide Signaling Pathway by Adrenal Glucocorticoids in Rat Brain: Focus on Phosphoinositide-Specific Phospholipase C and Inositol 1,4,5-Trisphosphate
G-Protein Sensitivity of Ligand Binding to Human Dopamine D2 and D3 Receptors Expressed in Escherichia coli: Clues for a Constrained D3 Receptor Structure
Cellular Uptake and Efficacy of Antisense Oligonucleotides against RNAs of Two Na+ Channel Isoforms
Identification of the Sites of Asparagine-Linked Glycosylation on the Human Thyrotropin Receptor and Studies on Their Role in Receptor Function and Expression
Chemotherapy, Antibiotics and Gene Therapy
Inhibition of Volume-Regulated and Calcium-Activated Chloride Channels by the Antimalarial Mefloquine
A Pharmacodynamic Analysis of Erythropoietin-Stimulated Reticulocyte Response in Phlebotomized Sheep
Inflammation and Immunopharmacology
Amelioration of Murine Experimental Colitis by Inhibition of Mucosal Addressin Cell Adhesion Molecule-1
Anti-Inflammatory and Antinociceptive Properties of BP 2-94, a Histamine H3-Receptor Agonist Prodrug
A Novel Phosphodiesterase Type 4 Inhibitor, YM976 (4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one), with Little Emetogenic Activity
Neuropharmacology
N-Acetylated alpha-Linked Acidic Dipeptidase Converts N-Acetylaspartylglutamate from a Neuroprotectant to a Neurotoxin
Comparison between Intraperitoneal and Oral Methylphenidate Administration: A Microdialysis and Locomotor Activity Study
Nicotinic Modulation of Mesoprefrontal Dopamine Neurons: Pharmacologic and Neuroanatomic Characterization
Effects of Acute and Subchronic Administration of Typical and Atypical Antipsychotic Drugs on the Neurotensin System of the Rat Brain
Incomplete, Asymmetric, and Route-Dependent Cross-Tolerance between Oxycodone and Morphine in the Dark Agouti Rat
Effects of Microdialyzed Oxotremorine, Carbachol, Epibatidine, and Scopolamine on Intraspinal Release of Acetylcholine in the Rat
Effects of Agonist-Antagonist Opioids in Humans Trained in a Hydromorphone/Not Hydromorphone Discrimination
Systemic Infusion of Naloxone Reduces Degeneration of Rat Substantia Nigral Dopaminergic Neurons Induced by Intranigral Injection of Lipopolysaccharide
Chlormethiazole: Effectiveness against Toxic Effects of Cocaine in Mice
Antinociceptive Effect of Pregabalin in Septic Shock-Induced Rectal Hypersensitivity in Rats
Gastric Effects of Cholecystokinin and Its Interaction with Leptin on Brainstem Neuronal Activity in Neonatal Rats
Retro-Inverso Prosaptide Peptides Retain Bioactivity, Are Stable In Vivo, and Are Blood-Brain Barrier Permeable
Sex- and Estrous Cycle-Related Differences in the Effects of Acute Antipsychotic Drug Administration on Neurotensin-Containing Neurons in the Rat Brain
Inverse Agonist Activity of Atypical Antipsychotic Drugs at Human 5-Hydroxytryptamine2C Receptors
Antisense-Mediated Down-Regulation of the Human Huntington Gene
Discovery of "Self-Synergistic" Spinal/Supraspinal Antinociception Produced by Acetaminophen (Paracetamol)
Effect of Phenylalanine and Its Metabolites on the Proliferation and Viability of Neuronal and Astroglial Cells: Possible Relevance in Maternal Phenylketonuria
Nitric Oxide Is Involved in Acetylcholinesterase Inhibitor-Induced Myopathy in Rats
Bupropion Is a Nicotinic Antagonist
Cannabinoid Agonist Signal Transduction in Rat Brain: Comparison of Cannabinoid Agonists in Receptor Binding, G-Protein Activation, and Adenylyl Cyclase Inhibition
Characterization of the Anxiolytic Properties of a Novel Neuroactive Steroid, Co 2-6749 (GMA-839; WAY-141839; 3alpha, 21-Dihydroxy-3beta-trifluoromethyl-19-nor-5beta-pregnan-20-one), a Selective Modulator of gamma-Aminobutyric AcidA Receptors
Nonpeptide Tachykinin Receptor Antagonists. II. Pharmacological and Pharmacokinetic Profile of SB-222200, a Central Nervous System Penetrant, Potent and Selective NK-3 Receptor Antagonist
Pharmacological Characterization of the Discriminative Stimulus Effects of the Potassium Channel Blocker 4-Aminopyridine in Rats
Transport of N-Acetylaspartate by the Na+-Dependent High-Affinity Dicarboxylate Transporter NaDC3 and Its Relevance to the Expression of the Transporter in the Brain
Effects of Chronic Ethanol Treatment on gamma-Aminobutyric AcidA and Glycine Receptors in Mouse Glycinergic Spinal Neurons
Temporal Changes in Metallothionein Gene Transcription in Rat Kidney and Liver: Relationship to Content of Mercury and Metallothionein Protein
Perspectives
Review of Mammalian DNA Repair and Translational Implications
Reproduction and Endocrinology
Estrogen Inhibition of Cystic Fibrosis Transmembrane Conductance Regulator-Mediated Chloride Secretion
Long-Term Aquaretic Efficacy of a Selective Nonpeptide V2-Vasopressin Receptor Antagonist, SR121463, in Cirrhotic Rats
Effect of Hydroxyeicosatetraenoic Acids on Furosemide-Sensitive Chloride Secretion in Rat Distal Colon
Inhibition of Thromboxane A2-Induced Cl- Secretion by Antidiarrhea Drug Loperamide in Isolated Rat Colon
Interaction and Transport of Thiazide Diuretics, Loop Diuretics, and Acetazolamide via Rat Renal Organic Anion Transporter rOAT2
Intestinal Type 2 Proteinase-Activated Receptors: Expression in Opioid-Sensitive Secretomotor Neural Circuits That Mediate Epithelial Ion Transport
