Annals ofPharmacology

Volume: 4 - Number: 32 - August 15, 2004

Outstanding

International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels: Potassium Channels

Interleukin-10 Therapy—Review of a New Approach

The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels

Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters

Absortion, Distribution, Metabolism and Excretion

In Vivo Mechanistic Studies on the Metabolic Activation of 2-Phenylpropionic Acid in Rat

In Vivo Modulation of Intestinal CYP3A Metabolism by P-Glycoprotein: Studies Using the Rat Single-Pass Intestinal Perfusion Model

Insulin and Glucagon Regulation of Glutathione S-Transferase Expression in Primary Cultured Rat Hepatocytes

Articles

Generation and Analysis of Constitutively Active and Physically Destabilized Mutants of the Human 1-Adrenoceptor

Genistein Inhibits Cardiac L-Type Ca2+ Channel Activity by a Tyrosine Kinase-Independent Mechanism

Glucocorticoid-Mediated Induction of CYP3A4 is Decreased by Disruption of a Protein: DNA Interaction Distinct from the Pregnane X Receptor Response Element

Glucuronidation of Dihydroartemisinin in Vivo and by Human Liver Microsomes and Expressed UDP-Glucuronosyltransferases

Glucuronides of Tea Catechins: Enzymology of Biosynthesis and Biological Activities

Identification of Interaction Sites of Cyclic Nucleotide Phosphodiesterase Type 3A with Milrinone and Cilostazol Using Molecular Modeling and Site-Directed Mutagenesis

Identification of the Extracellular Loop 2 as the Point of Interaction between the N Terminus of the Chemokine MIP-1 and Its CCR1 Receptor

Identification of the Human Liver Enzymes Involved in the Metabolism of the Antimigraine Agent Almotriptan

Inhibition and Activation of the Human Liver Microsomal and Human Cytochrome P450 3A4 Metabolism of Testosterone by Deployment-Related Chemicals

Inhibition of Cyclin-Dependent Kinase 2 by the Chk1-Cdc25A Pathway during the S-Phase Checkpoint Activated by Fludarabine: Dysregulation by 7-Hydroxystaurosporine

Inhibitory Effect of Fluvastatin on Lysophosphatidylcholine-Induced Nonselective Cation Current in Guinea Pig Ventricular Myocytes

Insights from a Three-Dimensional Model into Ligand Binding to Constitutive Active Receptor

International Union of Pharmacology XLIV. Nomenclature for the Oxoeicosanoid Receptor

Behaviour Pharmacology

Human Urocortin II, a Selective Agonist for the Type 2 Corticotropin-Releasing Factor Receptor, Decreases Feeding and Drinking in the Rat

Brief communicactions

Inhibition of Tetrodotoxin (TTX)-Resistant and TTX-Sensitive Neuronal Na+ Channels by the Secretolytic Ambroxol

Extensive review

GAF Domains: Two–Billion–Year–Old Molecular Switches that Bind Cyclic Nucleotides

Induction of Drug Metabolism: The Role of Nuclear Receptors

International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology

International Union of Pharmacology. XL. Compendium of Voltage-Gated Ion Channels: Calcium Channels

International Union of Pharmacology. XLI. Compendium of Voltage-Gated Ion Channels: Potassium Channels

International Union of Pharmacology. XLII. Compendium of Voltage-Gated Ion Channels: Cyclic Nucleotide-Modulated Channels

Gender Differences in the Membrane Transport of Endogenous and Exogenous Compounds

Interleukin-10 Therapy—Review of a New Approach

The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels

Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters

Gastrointestinal, hepatic, pulmonary and renal pharmacology

Increased Relaxant Action of Forskolin and Isoproterenol against Muscarinic Agonist-Induced Contractions in Smooth Muscle from M2 Receptor Knockout Mice

Inhibition of Cyclooxygenases Reduces Complement-Induced Glomerular Epithelial Cell Injury and Proteinuria in Passive Heymann Nephritis

Introduction

International Union of Pharmacology Nomenclature and Pharmacological Reviews

Neuropharmacology

Individual Differences in Cocaine-Induced Locomotor Sensitization in Low and High Cocaine Locomotor-Responding Rats Are Associated with Differential Inhibition of Dopamine Clearance in Nucleus Accumbens

Inhibition of P-Glycoprotein by Newer Antidepressants

Short communications

Homotropic Versus Heterotopic Cooperativity of Cytochrome P450eryF: A Substrate Oxidation and Spectral Titration Study

Toxicology

Hypothalamic-Pituitary-Thyroid Axis and Sympathetic Nervous System Involvement in Hyperthermia Induced by 3,4-Methylenedioxymethamphetamine (Ecstasy)

Viewpoint

GIRK Channel Trafficking: Different Paths for Different Family Members

I’ll Simply Die Without My Calcium: Ca2+ Signaling and Surviving Cellular Stress