Articles
Neurotensin Induces Tyrosine Hydroxylase Gene Activation through Nitric Oxide and Protein Kinase C Signaling Pathways
N-Glucuronidation of Nicotine and Cotinine in Human: Formation of Cotinine Glucuronide in Liver Microsomes and Lack of Catalysis by 10 Examined UDP-Glucuronosyltransferases
Nuclear Pregnane X Receptor and Constitutive Androstane Receptor Regulate Overlapping but Distinct Sets of Genes Involved in Xenobiotic Detoxification
Pharmacokinetics and Metabolism of a COX-2 Inhibitor, Valdecoxib, in Mice
Pharmacokinetics, Metabolic Stability, and Subcutaneous Bioavailability of a Genetically Engineered Analog of DcR3, FLINT [DcR3(R218Q)], in Cynomolgus Monkeys and Mice
Regulation of Human CYP2C9 by the Constitutive Androstane Receptor: Discovery of a New Distal Binding Site
Regulation of Platinum-Compound Cytotoxicity by the c-Jun N-Terminal Kinase and c-Jun Signaling Pathway in Small-Cell Lung Cancer Cells
Restoration of Human -Globin Gene Expression in Murine and Human IVS2-654 Thalassemic Erythroid Cells by Free Uptake of Antisense Oligonucleotides
Retention of Transporter Activities in Cryopreserved, Isolated Rat Hepatocytes
Role of the Human Herpesvirus 6 U69-Encoded Kinase in the Phosphorylation of Ganciclovir
Segmental Intestinal Transporters and Metabolic Enzymes on Intestinal Drug Absorption
Sexual Dimorphism and Tissue Specificity in the Expression of CYP4F Forms in Sprague Dawley Rats
Cardiovascular pharmacology
N-[3-(R)-Tetrahydrofuranyl]-6-aminopurine Riboside, an A1 Adenosine Receptor Agonist, Antagonizes Catecholamine-Induced Lipolysis without Cardiovascular Effects in Awake Rats
Role of Cytochrome P4501B1 in Benzo[a]pyrene Bioactivation to DNA-Binding Metabolites in Mouse Vascular Smooth Muscle Cells: Evidence from 32P-Postlabeling for Formation of 3-Hydroxybenzo[a]pyrene and Benzo[a]pyrene-3,6-quinone as Major Proximate Genotoxi
Sexual Dimorphism in Cafeteria Diet-Induced Hypertension Is Associated with Gender-Related Difference in Renal Leptin Receptor Down-Regulation
Extensive Reviews
Neurobiology of Relapse to Heroin and Cocaine Seeking: A Review
Protein Origami: Therapeutic Rescue of Misfolded Gene Products
RNA Interference in Biology and Medicine
Gastrointestinal, hepatic, pulmonary and renal
Renal Function in a Rat Model of Analgesic Nephropathy: Effect of Chloroquine
Inflammation and Immunopharmacology
Neurokinin-1 Receptor Antagonists CP-96,345 and L-733,060 Protect Mice from Cytokine-Mediated Liver Injury
Net Results
Sites of interest on the World Wide Web–edited by Rick Neubig
Neuropharmacology
Pharmacological Characterization of a Novel Nonpeptide Antagonist Radioligand, (±)-N-[2-Methyl-4-methoxyphenyl]-1-(1-(methoxymethyl) propyl)-6-methyl-1H-1,2,3-triazolo[4,5-c]pyridin-4-amine ([3H]SN003) for Corticotropin-Releasing Factor1 Receptors
Piribedil Enhances Frontocortical and Hippocampal Release of Acetylcholine in Freely Moving Rats by Blockade of 2A-Adrenoceptors: A Dialysis Comparison to Talipexole and Quinelorane in the Absence of Acetylcholinesterase Inhibitors
Receptor Occupancy of Nonpeptide Corticotropin-Releasing Factor 1 Antagonist DMP696: Correlation with Drug Exposure and Anxiolytic Efficacy
Repeated Exposures to Subthreshold Doses of Chlorpyrifos in Rats: Hippocampal Damage, Impaired Axonal Transport, and Deficits in Spatial Learning
Stress-Induced Suppression of the Immune System after Withdrawal from Chronic Cocaine
Perspectives in Pharmacology
Nucleus Accumbens Dopamine and the Regulation of Effort in Food-Seeking Behavior: Implications for Studies of Natural Motivation, Psychiatry, and Drug Abuse
Pharmacogenomics of Human UDP-Glucuronosyltransferases and Irinotecan Toxicity
Viewpoint
p53 Moves Into Control of Cell Morphology
STEPping into Position: A New Player in the NMDA Receptor Game
