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Absortion, Distribution, Metabolism and Excretion

Gene Expression in the Human Intestine and Correlation with Oral Valacyclovir Pharmacokinetic Parameters

Genetic Variability at the Human FMO1 Locus: Significance of a Basal Promoter Yin Yang 1 Element Polymorphism (FMO1*6)

Human Hepatic CYP2E1 Expression during Development

Noticias del día

Behaviour Pharmacology

GABAergic Systems Modulate Nicotinic Receptor-Mediated Seizures in Mice

Inhibition of Microglial Activation Attenuates the Development but Not Existing Hypersensitivity in a Rat Model of Neuropathy

Cardiovascular

Glycoprotein IIb/IIIa Receptor Antagonist (2S)-2-[(2-Naphthyl-sulfonyl)amino]-3-{[2-({4-(4-piperidinyl)-2-[2-(4-piperidinyl)ethyl] butanoyl}amino)acetyl]amino}propanoic Acid Dihydrochloride (CRL42796), in Combination with Aspirin and/or Enoxaparin, Preven

Inhibition of Canine (NCX1.1) and Drosophila (CALX1.1) Na+-Ca2+ Exchangers by 7-Chloro-3,5-dihydro-5-phenyl-1H-4,1-benzothiazepine-2-one (CGP-37157)

Inhibitors of 20-Hydroxyeicosatetraenoic Acid Reduce Renal Vasoconstrictor Responsiveness

Interleukin-2 Increases Activity of Sarcoplasmic Reticulum Ca2+-ATPase, but Decreases Its Sensitivity to Calcium in Rat Cardiomyocytes

Diabetes e Incretinas

Cellular y Molecular

Generation and Characterization of Highly Constitutive Active Histamine H3 Receptors

Green Tea Polyphenol Causes Differential Oxidative Environments in Tumor versus Normal Epithelial Cells

Identification of Residues That Confer -Conotoxin-PnIA Sensitivity on the 3 Subunit of Neuronal Nicotinic Acetylcholine Receptors

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Endocrine and reproduction

Functional Melatonin Receptors in Rat Ovaries at Various Stages of the Estrous Cycle

Extensive review

Gender Differences in the Membrane Transport of Endogenous and Exogenous Compounds

Generation of the Melatonin Endocrine Message in Mammals: A Review of the Complex Regulation of Melatonin Synthesis by Norepinephrine, Peptides, and Other Pineal Transmitters

Impact of Drug Transporter Studies on Drug Discovery and Development

Interleukin-10 Therapy—Review of a New Approach

Interleukins in Atherosclerosis: Molecular Pathways and Therapeutic Potential

International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors

Diabetes e Incretinas

Gastrointestinal, hepatic, pulmonary and renal

Hepatocyte Growth Factor Facilitates Colonic Mucosal Repair in Experimental Ulcerative Colitis in Rats

Interactions among Three Classes of Mediators Explain Antigen-Induced Bronchoconstriction in the Isolated Perfused and Ventilated Guinea Pig Lung

Inflammation and Immunopharmacology

In Vivo Efficacy in Airway Disease Models of N-(3,5-Dichloropyrid-4-yl)-[1-(4-fluorobenzyl)-5-hydroxy-indole-3-yl]-glyoxylic Acid Amide (AWD 12-281), a Selective Phosphodiesterase 4 Inhibitor for Inhaled Administration

Inhibition of Inflammation and Remodeling by Roflumilast and Dexamethasone in Murine Chronic Asthma

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Neuropharmacology

Group II Metabotropic and -Amino-3-hydroxy-5-methyl-4-isoxazole Propionate (AMPA)/Kainate Glutamate Receptors Regulate the Deficit in Brain Reward Function Associated with Nicotine Withdrawal in Rats

Hyperlocomotive and Discriminative Stimulus Effects of Cocaine Are Under the Control of Serotonin2C (5-HT2C) Receptors in Rat Prefrontal Cortex

In Vitro Characterization of Ephedrine-Related Stereoisomers at Biogenic Amine Transporters and the Receptorome Reveals Selective Actions as Norepinephrine Transporter Substrates

Increased Expression of Vanilloid Receptor 1 on Myelinated Primary Afferent Neurons Contributes to the Antihyperalgesic Effect of Capsaicin Cream in Diabetic Neuropathic Pain in Mice

Interaction of Antiepileptic Drugs with Human P-Glycoprotein in Vitro

Diabetes e Incretinas

Perspectives in Pharmacology

Inflammation and Drug Idiosyncrasy—Is There a Connection?

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