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Absortion, Distribution, Metabolism and Excretion

Threonine-205 in the F Helix of P450 2B1 Contributes to Androgen 16-Hydroxylation Activity and Mechanism-Based Inactivation

Behaviour Pharmacology

Relative Efficacy of Buprenorphine, Nalbuphine and Morphine in Opioid-Treated Rhesus Monkeys Discriminating Naltrexone

Temporal Effects of Stress by Immobilization and Sensitivity of the Isolated Rat Pacemaker to Isoproterenol: Roles of Corticosterone, Neuronal Uptake, and -Adrenergic Homogeneity

The Reinforcing Efficacy of Psychostimulants in Rhesus Monkeys: The Role of Pharmacokinetics and Pharmacodynamics

Topical Capsaicin-Induced Allodynia in Unanesthetized Primates: Pharmacological Modulation

Wake-Promoting Actions of Dopamine D1 and D2 Receptor Stimulation

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Cardiovascular

Pilot Intervention: Aerosolized Adrenomedullin Reduces Pulmonary Hypertension

S-Nitrosating Nitric Oxide Donors Induce Long-Lasting Inhibition of Contraction in Isolated Arteries

Cellular y Molecular

PAT5A: A Partial Agonist of Peroxisome Proliferator-Activated Receptor Is a Potent Antidiabetic Thiazolidinedione Yet Weakly Adipogenic

The Cytoplasmic Domain of Alzheimer's Amyloid- Protein Precursor Causes Sustained Apoptosis Signal-Regulating Kinase 1/c-Jun NH2-Terminal Kinase-Mediated Neurotoxic Signal via Dimerization

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Endocrine and reproduction

The Role of I1-Imidazoline and 2-Adrenergic Receptors in the Modulation of Glucose Metabolism in the Spontaneously Hypertensive Obese Rat Model of Metabolic Syndrome X

Extensive review

Pharmacogenetics of Anticancer Drug Sensitivity in Non-Small Cell Lung Cancer

Pharmacological Agents That Directly Modulate Insulin Secretion

Specific Targeted Therapy of Chronic Myelogenous Leukemia with Imatinib

The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy")

The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels

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Gastrointestinal, hepatic, pulmonary and renal

Prevention of Ethanol-Induced Liver Injury in Rats by an Agonist of Peroxisome Proliferator-Activated Receptor-, Pioglitazone

Renal Action of Acute Chloroquine and Paracetamol Administration in the Anesthetized, Fluid-Balanced Rat

Stimulatory Action of Itopride Hydrochloride on Colonic Motor Activity in Vitro and in Vivo

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Inflammation and Immunopharmacology

Potency and Specificity of the Pharmacological Action of a New, Antiasthmatic, Topically Administered Soft Steroid, Etiprednol Dicloacetate (BNP-166)

Reversal of Multiple Drug Resistance in Cholangiocarcinoma by the Glutathione S-Transferase--Specific Inhibitor O1-Hexadecyl--glutamyl-S-benzylcysteinyl-D-phenylglycine Ethylester

The Orally Available Spleen Tyrosine Kinase Inhibitor 2-[7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide Dihydrochloride (BAY 61-3606) Blocks Antigen-Induced Airway Inflammation in Rodents

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Neuropharmacology

Potentiation of N-Methyl-D-aspartate-Induced Currents by the Nootropic Drug Nefiracetam in Rat Cortical Neurons

Regulation of Septo-Hippocampal Activity by 5-Hydroxytryptamine2C Receptors

Role of Na+,K+-ATPase in Morphine-Induced Antinociception

Role of the Nitric-Oxide Synthase Isoforms during Morphine-Induced Hyperthermia in Rats

Sites of Excitatory and Inhibitory Actions of Alcohols on Neuronal 24 Nicotinic Acetylcholine Receptors

The Endogenous Cannabinoid Anandamide Inhibits 7 Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes

The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy

Treatment of Adverse Effects of Excessive Phencyclidine Exposure in Rats with a Minimal Dose of Monoclonal Antibody

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Perspectives in Pharmacology

The Cholinergic Hypothesis of Age and Alzheimer's Disease-Related Cognitive Deficits: Recent Challenges and Their Implications for Novel Drug Development

Toxicology

Oxidative Stress-Induced Homologous Recombination As a Novel Mechanism for Phenytoin-Initiated Toxicity

Ranitidine Treatment during a Modest Inflammatory Response Precipitates Idiosyncrasy-Like Liver Injury in Rats

Role of Cysteine S-Conjugate -Lyase in the Metabolism of Cisplatin

Scavenging Peroxynitrite with Glutathione Promotes Regeneration and Enhances Survival during Acetaminophen-Induced Liver Injury in Mice

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