Absortion, Distribution, Metabolism and Excretion
Threonine-205 in the F Helix of P450 2B1 Contributes to Androgen 16-Hydroxylation Activity and Mechanism-Based Inactivation
Behaviour Pharmacology
Relative Efficacy of Buprenorphine, Nalbuphine and Morphine in Opioid-Treated Rhesus Monkeys Discriminating Naltrexone
Temporal Effects of Stress by Immobilization and Sensitivity of the Isolated Rat Pacemaker to Isoproterenol: Roles of Corticosterone, Neuronal Uptake, and -Adrenergic Homogeneity
The Reinforcing Efficacy of Psychostimulants in Rhesus Monkeys: The Role of Pharmacokinetics and Pharmacodynamics
Topical Capsaicin-Induced Allodynia in Unanesthetized Primates: Pharmacological Modulation
Wake-Promoting Actions of Dopamine D1 and D2 Receptor Stimulation
Cardiovascular
Pilot Intervention: Aerosolized Adrenomedullin Reduces Pulmonary Hypertension
S-Nitrosating Nitric Oxide Donors Induce Long-Lasting Inhibition of Contraction in Isolated Arteries
Cellular y Molecular
PAT5A: A Partial Agonist of Peroxisome Proliferator-Activated Receptor Is a Potent Antidiabetic Thiazolidinedione Yet Weakly Adipogenic
The Cytoplasmic Domain of Alzheimer's Amyloid- Protein Precursor Causes Sustained Apoptosis Signal-Regulating Kinase 1/c-Jun NH2-Terminal Kinase-Mediated Neurotoxic Signal via Dimerization
Endocrine and reproduction
The Role of I1-Imidazoline and 2-Adrenergic Receptors in the Modulation of Glucose Metabolism in the Spontaneously Hypertensive Obese Rat Model of Metabolic Syndrome X
Extensive review
Pharmacogenetics of Anticancer Drug Sensitivity in Non-Small Cell Lung Cancer
Pharmacological Agents That Directly Modulate Insulin Secretion
Specific Targeted Therapy of Chronic Myelogenous Leukemia with Imatinib
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy")
The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels
Gastrointestinal, hepatic, pulmonary and renal
Prevention of Ethanol-Induced Liver Injury in Rats by an Agonist of Peroxisome Proliferator-Activated Receptor-, Pioglitazone
Renal Action of Acute Chloroquine and Paracetamol Administration in the Anesthetized, Fluid-Balanced Rat
Stimulatory Action of Itopride Hydrochloride on Colonic Motor Activity in Vitro and in Vivo
Inflammation and Immunopharmacology
Potency and Specificity of the Pharmacological Action of a New, Antiasthmatic, Topically Administered Soft Steroid, Etiprednol Dicloacetate (BNP-166)
Reversal of Multiple Drug Resistance in Cholangiocarcinoma by the Glutathione S-Transferase--Specific Inhibitor O1-Hexadecyl--glutamyl-S-benzylcysteinyl-D-phenylglycine Ethylester
The Orally Available Spleen Tyrosine Kinase Inhibitor 2-[7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide Dihydrochloride (BAY 61-3606) Blocks Antigen-Induced Airway Inflammation in Rodents
Neuropharmacology
Potentiation of N-Methyl-D-aspartate-Induced Currents by the Nootropic Drug Nefiracetam in Rat Cortical Neurons
Regulation of Septo-Hippocampal Activity by 5-Hydroxytryptamine2C Receptors
Role of Na+,K+-ATPase in Morphine-Induced Antinociception
Role of the Nitric-Oxide Synthase Isoforms during Morphine-Induced Hyperthermia in Rats
Sites of Excitatory and Inhibitory Actions of Alcohols on Neuronal 24 Nicotinic Acetylcholine Receptors
The Endogenous Cannabinoid Anandamide Inhibits 7 Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy
Treatment of Adverse Effects of Excessive Phencyclidine Exposure in Rats with a Minimal Dose of Monoclonal Antibody
Perspectives in Pharmacology
The Cholinergic Hypothesis of Age and Alzheimer's Disease-Related Cognitive Deficits: Recent Challenges and Their Implications for Novel Drug Development
Toxicology
Oxidative Stress-Induced Homologous Recombination As a Novel Mechanism for Phenytoin-Initiated Toxicity
Ranitidine Treatment during a Modest Inflammatory Response Precipitates Idiosyncrasy-Like Liver Injury in Rats
Role of Cysteine S-Conjugate -Lyase in the Metabolism of Cisplatin
Scavenging Peroxynitrite with Glutathione Promotes Regeneration and Enhances Survival during Acetaminophen-Induced Liver Injury in Mice