Absortion, Distribution, Metabolism and Excretion
Amino Acid Ester Prodrugs of 2-Bromo-5,6-dichloro-1-(-D-ribofuranosyl)benzimidazole Enhance Metabolic Stability in Vitro and in Vivo
Bile Salt Export Pump (BSEP/ABCB11) Can Transport a Nonbile Acid Substrate, Pravastatin
Comparative Pharmacophore Modeling of Organic Anion Transporting Polypeptides: A Meta-Analysis of Rat Oatp1a1 and Human OATP1B1
Behavioral pharmacology
Characterization in Rats of the Anxiolytic Potential of ELB139 [1-(4-Chlorophenyl)-4-piperidin-1-yl-1,5-dihydro-imidazol-2-on], a New Agonist at the Benzodiazepine Binding Site of the GABAA Receptor
Characterization of the Discriminative Stimulus Effects of the Neuroactive Steroid Pregnanolone in DBA/2J and C57BL/6J Inbred Mice
Cardiovascular
Arachidonic Acid Epoxygenase Metabolites Stimulate Endothelial Cell Growth and Angiogenesis via Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways
Differential Distribution of Functional 1-Adrenergic Receptor Subtypes along the Rat Tail Artery
Gastroenterology, Hepatic, Renal and Lung
Long-Term Treatment of Bile Duct-Ligated Rats with Rapamycin (Sirolimus) Significantly Attenuates Liver Fibrosis: Analysis of the Underlying Mechanisms
Cholinergic Stimulation of Amylase Secretion from Pancreatic Acinar Cells Studied with Muscarinic Acetylcholine Receptor Mutant Mice
Demonstration of a Specific Site of Covalent Labeling of the Human Motilin Receptor Using a Biologically Active Photolabile Motilin Analog
Regulation of Human Hepatocytes by P2Y Receptors: Control of Glycogen Phosphorylase, Ca2+, and Mitogen-Activated Protein Kinases
Gastrointestinal, hepatic, pulmonary and renal pharmacology
A Farnesoid X Receptor-Small Heterodimer Partner Regulatory Cascade Modulates Tissue Metalloproteinase Inhibitor-1 and Matrix Metalloprotease Expression in Hepatic Stellate Cells and Promotes Resolution of Liver Fibrosis
Barakol Extracted from Cassia siamea Stimulates Chloride Secretion in Rat Colon
Inflammation and Immunopharmacology
A Novel Celecoxib Derivative Potently Induces Apoptosis of Human Synovial Fibroblasts
Angiopoietin-2 Causes Inflammation in Vivo by Promoting Vascular Leakage
Neuropharmacology
µ Opioid Receptor Coupling to Gi/o Proteins Increases during Postnatal Development in Rat Brain
2 Adrenergic Receptor-Mediated Enhancement of Hippocampal CA3 Network Activity
Binding Profile of the Endogenous Novel Heptapeptide Met-Enkephalin-Gly-Tyr in Zebrafish and Rat Brain
Brain Uptake Kinetics of Nicotine and Cotinine after Chronic Nicotine Exposure
Cocaine Up-Regulates Fra-2 and -1 Receptor Gene and Protein Expression in Brain Regions Involved in Addiction and Reward
Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity
Toxicology
Consequences of Abrupt Glutathione Depletion in Murine Clara Cells: Ultrastructural and Biochemical Investigations into the Role of Glutathione Loss in Naphthalene Cytotoxicity
