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Absortion, Distribution, Metabolism and Excretion

The Lymph Lipid Precursor Pool Is a Key Determinant of Intestinal Lymphatic Drug Transport

Behavioral pharmacology

Analysis of the Antinociceptive Effect of the Flavonoid Myricitrin: Evidence for a Role of the L-Arginine-Nitric Oxide and Protein Kinase C Pathways

Cardiovascular

Sphingosine 1-Phosphate Induces Endothelial Nitric-Oxide Synthase Activation through Phosphorylation in Human Corpus Cavernosum

Tachycardia Caused by A2A Adenosine Receptor Agonists Is Mediated by Direct Sympathoexcitation in Awake Rats

An Increase in Late Sodium Current Potentiates the Proarrhythmic Activities of Low-Risk QT-Prolonging Drugs in Female Rabbit Hearts

Attenuation of Vascular Smooth Muscle Cell Proliferation by 1-Cyclohexyl-3-dodecyl Urea Is Independent of Soluble Epoxide Hydrolase Inhibition

Diabetes e Incretinas

Cellular y Molecular

Antimelanoma Activity of Apoptogenic Carbonyl Scavengers

Gastroenterology, Hepatic, Renal and Lung

Roles of Cyclooxygenase-2 and Prostacyclin/IP Receptors in Mucosal Defense against Ischemia/Reperfusion Injury in Mouse Stomach

Selective Inhibition of Phosphodiesterase-4 Ameliorates Chronic Colitis and Prevents Intestinal Fibrosis

Sex Differences in the mRNA, Protein, and Functional Expression of Organic Anion Transporter (Oat) 1, Oat3, and Organic Cation Transporter (Oct) 2 in Rabbit Renal Proximal Tubules

The Relaxant Activity of 4,7-Dimethyl-1,2,5-oxadiazolo[3,4-d]-pyridazine 1,5,6-Trioxide in the Mouse Corpus Cavernosum

A Xanthine-Based Epithelium-Dependent Airway Relaxant KMUP-3 (7-[2-[4-(4-Nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) Increases Respiratory Performance and Protects against Tumor Necrosis Factor--Induced Tracheal Contraction, Involving Nitric Oxi

Adenosine A1 Receptor Antagonist Blunts Urinary Potassium Excretion, but Not Renal Hemodynamic Effects, Induced by Carbonic Anhydrase Inhibitor in Rats

Diabetes e Incretinas

Inflammation and Immunopharmacology

Opioid Receptors Stimulate Akt-Dependent Phosphorylation of c-jun in T Cells

A Novel Cannabinoid Peripheral Cannabinoid Receptor-Selective Inverse Agonist Blocks Leukocyte Recruitment in Vivo

Neuropharmacology

Apolipoprotein E-Derived Peptides Block 7 Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes

Noticias del día

Perspectives in Pharmacology

Striatal 6* Nicotinic Acetylcholine Receptors: Potential Targets for Parkinson\'s Disease Therapy

Reviews

Signaling Pathways Regulating Gene Expression, Neuroplasticity, and Neurotrophic Mechanisms in the Action of Antidepressants: A Critical Overview

Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol

Uptake Pathways and Subsequent Intracellular Trafficking in Nonviral Gene Delivery

Diabetes e Incretinas

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