Behavioral pharmacology
Antinociceptive Pharmacology of N-[[4-(4,5-Dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide, Fumarate (LF22-0542), a Novel Nonpeptidic Bradykinin B1 Receptor Antagonist
Endogenous Orphanin FQ/Nociceptin Is Involved in the Development of Morphine Tolerance
Cardiovascular
Augmented Endothelium-Derived Hyperpolarizing Factor-Mediated Relaxations Attenuate Endothelial Dysfunction in Femoral and Mesenteric, but Not in Carotid Arteries from Type I Diabetic Rats
Blocking Late Sodium Current Reduces Hydrogen Peroxide-Induced Arrhythmogenic Activity and Contractile Dysfunction
Central Adenosine Signaling Plays a Key Role in Centrally Mediated Hypotension in Conscious Aortic Barodenervated Rats
Differentiation of Arrhythmia Risk of the Antibacterials Moxifloxacin, Erythromycin, and Telithromycin Based on Analysis of Monophasic Action Potential Duration Alternans and Cardiac Instability
Cellular y Molecular
Augmentation of Cav3.2 T-Type Calcium Channel Activity by cAMP-Dependent Protein Kinase A
Chemotherapy, Antibiotics and Gene Therapy
Blockade of Angiogenesis by Small Molecule Antagonists to Protease-Activated Receptor-1: Association with Endothelial Cell Growth Suppression and Induction of Apoptosis
Endocrine and diabetes
Cilostazol Protects Diabetic Rats from Vascular Inflammation via Nuclear Factor-B-Dependent Down-Regulation of Vascular Cell Adhesion Molecule-1 Expression
Differential Modulation of Cav1.2 and Cav1.3-Mediated Glucose-Stimulated Insulin Secretion by cAMP in INS-1 Cells: Distinct Roles for Exchange Protein Directly Activated by cAMP 2 (Epac2) and Protein Kinase A
Inflammation, immuno-pharmacology, and asthma
A Selective p38 Mitogen-Activated Protein Kinase Inhibitor Reverses Cartilage and Bone Destruction in Mice with Collagen-Induced Arthritis
Carcinogen and Anticancer Drug Transport by Mrp2 in Vivo: Studies Using Mrp2 (Abcc2) Knockout Mice
Glycogen Synthase Kinase-3 Inhibition Reduces Secondary Damage in Experimental Spinal Cord Trauma
Neuropharmacology
Biphenyl-indanone A, a Positive Allosteric Modulator of the Metabotropic Glutamate Receptor Subtype 2, Has Antipsychotic- and Anxiolytic-Like Effects in Mice
Buprenorphine Activates µ and Opioid Receptor Like-1 Receptors Simultaneously, but the Analgesic Effect Is Mainly Mediated by µ Receptor Activation in the Rat Formalin Test
Differential Regulation of Mesolimbic 3/62 and 42 Nicotinic Acetylcholine Receptor Sites and Function after Long-Term Oral Nicotine to Monkeys
Effects of Anesthetics on Mutant N-Methyl-D-Aspartate Receptors Expressed in Xenopus Oocytes
Perspectives in Pharmacology
Alcohol Use, Vascular Disease, and Lipid-Lowering Drugs
Toxicology
Bioactive Properties of Iron-Containing Carbon Monoxide-Releasing Molecules
Enhanced Xenobiotic-Induced Hepatotoxicity and Kupffer Cell Activation by Restraint-Induced Stress
