Behavioral pharmacology
Relative Reinforcing Effects of Cocaine, Remifentanil, and Their Combination in Rhesus Monkeys
Cardiovascular
Improved Left Ventricular Function and Reduced Necrosis after Myocardial Ischemia/Reperfusion in Rabbits Treated with Ranolazine, an Inhibitor of the Late Sodium Channel
Increased RhoA/Rho-Kinase Signaling Mediates Spontaneous Tone in Aorta from Angiotensin II-Induced Hypertensive Rats
Induction of Heme Oxygenase-1 Is Involved in Carbon Monoxide-Mediated Central Cardiovascular Regulation
N6-(3-Iodobenzyl)-adenosine-5\'-N-methylcarboxamide Confers Cardioprotection at Reperfusion by Inhibiting Mitochondrial Permeability Transition Pore Opening via Glycogen Synthase Kinase 3
Pleiotropic Effects of the -Adrenoceptor Blocker Carvedilol on Calcium Regulation during Oxidative Stress-Induced Apoptosis in Cardiomyocytes
Cellular y Molecular
p53 Suppression of Arsenite-Induced Mitotic Catastrophe Is Mediated by p21CIP1/WAF1
Protein Kinase C Mediates Platelet-Induced Breast Cancer Cell Invasion
Chemotherapy, Antibiotics and Gene Therapy
Inhibition of Protein Kinase c-Src Reduces the Incidence of Breast Cancer Metastases and Increases Survival in Mice: Implications for Therapy
Endocrine and diabetes
Preventive and Therapeutic Potential of p38-Selective Mitogen-Activated Protein Kinase Inhibitor in Nonobese Diabetic Mice with Type 1 Diabetes
Gastroenterology, Hepatic, Renal and Lung
Immunomodulatory Therapeutic Effect of Glatiramer Acetate on Several Murine Models of Inflammatory Bowel Disease
Inflammation, immuno-pharmacology, and asthma
Inhibition of Nuclear Factor-B Enhances the Capacity of Immature Dendritic Cells to Induce Antigen-Specific Tolerance in Experimental Autoimmune Encephalomyelitis
Nuclear Factor-B-Independent Anti-Inflammatory Action of Salicylate in Human Endothelial Cells: Induction of Heme Oxygenase-1 by the c-Jun N-Terminal Kinase/Activator Protein-1 Pathway
Metabolism, transport, and pharmacogenomics
Metabolism of Efavirenz and 8-Hydroxyefavirenz by P450 2B6 Leads to Inactivation by Two Distinct Mechanisms
Paclitaxel and Docetaxel Stimulation of Doxorubicinol Formation in the Human Heart: Implications for Cardiotoxicity of Doxorubicin-Taxane Chemotherapies
Neuropharmacology
Interaction of Functionalized Superparamagnetic Iron Oxide Nanoparticles with Brain Structures
Pharmacological Evaluation of Cannabinoid Receptor Ligands in a Mouse Model of Anxiety: Further Evidence for an Anxiolytic Role for Endogenous Cannabinoid Signaling
Physiological and Biophysical Factors That Influence Alzheimer\'s Disease Amyloid Plaque Targeting of Native and Putrescine Modified Human Amyloid 40
Toxicology
Nitroglycerin Attenuates Human Endothelial Progenitor Cell Differentiation, Function, and Survival
Paradoxical Effects of Hydrogen Peroxide on Human Airway Anion Secretion