Behavioral pharmacology
WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-Octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Preclinical Antipsychotic-Like Activity
Cardiovascular
The Nitric Oxide-Donating Pravastatin Derivative, NCX 6550 [(1S-[1(S*, S*), 2, 6, 8-(R*), 8a]]-1,2,6,7,8,8a-Hexahydro-, , 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphtalene-heptanoic Acid 4-(Nitrooxy)butyl Ester)], Reduces Splenocyte Adhesion and
Endocrine and diabetes
The Thyroid Disruptor 1,1,1-Trichloro-2,2-Bis(p-Chlorophenyl)-Ethane Appears to Be an Uncompetitive Inverse Agonist for the Thyrotropin Receptor
Gastroenterology, Hepatic, Renal and Lung
The Extracellular cAMP-Adenosine Pathway Significantly Contributes to the in Vivo Production of Adenosine
The Nuclear Receptor Constitutively Active/Androstane Receptor Regulates Type 1 Deiodinase and Thyroid Hormone Activity in the Regenerating Mouse Liver
The Prevention of Colitis by E Prostanoid Receptor 4 Agonist through Enhancement of Epithelium Survival and Regeneration
Metabolism, transport and pharmacogenomics
The Contribution of Intestinal UDP-Glucuronosyltransferases in Modulating 7-Ethyl-10-hydroxy-camptothecin (SN-38)-Induced Gastrointestinal Toxicity in Rats
Transport, Metabolism, and in Vivo Population Pharmacokinetics of the Chloro Benztropine Analogs, a Class of Compounds Extensively Evaluated in Animal Models of Drug Abuse
Valproic Acid Is Not a Substrate for P-glycoprotein or Multidrug Resistance Proteins 1 and 2 in a Number of in Vitro and in Vivo Transport Assays
Neuropharmacology
The Experimental Alzheimer\'s Disease Drug Posiphen [(+)-Phenserine] Lowers Amyloid- Peptide Levels in Cell Culture and Mice
Two Protein Trafficking Processes at Motor Nerve Endings Unveiled by Botulinum Neurotoxin E
Use-Dependent Block by Lidocaine but Not Amitriptyline Is More Pronounced in Tetrodotoxin (TTX)-Resistant Nav1.8 Than in TTX-Sensitive Na+ Channels