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Clinical Implications of the Basic Investigation

Genes, Microbes, and T Cells — New Therapeutic Targets in Crohn's Disease

Hepatic Diseases — Hitting the Target with Inhibitory RNAs

Editorial

Epidermal Growth Factor for Ulcerative Colitis

Helicobacter pylori — Not a Good Bug after All

Hepatitis B e Antigen — The Dangerous Endgame of Hepatitis B

Diabetes e Incretinas

Hormones and Signal

Enhanced calcium signaling and acid secretion in parietal cells isolated from gastrin-deficient mice

Erk1/2- and p38 MAP kinase-dependent phosphorylation and activation of cPLA2 by m3 and m2 receptors

Gastric atrial natriuretic peptide regulates endocrine secretion in antrum and fundus of human and rat stomach

Heat shock induces intestinal-type alkaline phosphatase in rat IEC-18 cells

Hemorrhage induces the rapid development of hepatic insulin resistance

Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action

IGF-I elicits growth of human intestinal smooth muscle cells by activation of PI3K, PDK-1, and p70S6 kinase

Impaired Ras membrane association and activation in PPAR knockout mice after partial hepatectomy

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Inflammation/immunity y/ mediators

Effects of NF-B inhibition on mesenteric ischemia-reperfusion injury

Exposure to schistosome eggs protects mice from TNBS-induced colitis

Impairment of TGF- signaling in T cells increases susceptibility to experimental autoimmune hepatitis in mice

Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis

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Liver and biliary tract

Fatty acid binding protein is a major determinant of hepatic pharmacokinetics of palmitate and its metabolites

Mucosal Biology

Hepatic inflammatory mediators contribute to intestinal damage in necrotizing enterocolitis

Neuroregulation and motility

Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection

Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying

High-fat diet effects on gut motility, hormone, and appetite responses to duodenal lipid in healthy men

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Original Articles

Efficacy and Safety of Imatinib Mesylate in Advanced Gastrointestinal Stromal Tumors

Endoscopic Ligation Compared with Combined Treatment with Nadolol and Isosorbide Mononitrate to Prevent Recurrent Variceal Bleeding

Epidermal Growth Factor Enemas with Oral Mesalamine for Mild-to-Moderate Left-Sided Ulcerative Colitis or Proctitis

Estrogen plus Progestin and Colorectal Cancer in Postmenopausal Women

Extended Transthoracic Resection Compared with Limited Transhiatal Resection for Adenocarcinoma of the Esophagus

Helicobacter pylori Infection and the Development of Gastric Cancer

Hepatitis B e Antigen and the Risk of Hepatocellular Carcinoma

Immunoproliferative Small Intestinal Disease Associated with Campylobacter jejuni

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Translational physiology

Effects of a -opioid agonist, asimadoline, on satiation and GI motor and sensory functions in humans

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