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- HEMOPHILIA B: -Merry christmas for patients with hemophilia B
Hemophilia B (also known as Christmas disease) is due to deficiency of coagulation factor IX (FIX). In this issue of the Journal, Nathwani et al. report the first unequivocal evidence of ...
- HEMOFILIA B: -Adenovirus-associated virus vector–mediated gene transfer in hemophilia B
Hemophilia B is an X-linked bleeding disorder that results from a defect in the gene encoding coagulation factor IX (FIX), a serine protease that is critical for blood clotting. Persons with ...
- MULTIPLE MYELOMA: -Mayo Clinic: How patients will respond to immunomodulator therapy for multiple myeloma
SAN DIEGO -- Research on the same protein that was a primary mediator of the birth defects caused by thalidomide now holds hope in the battle against multiple myeloma, says the study's senior ...
- REMISSSION OF CHRONIC LYMPHOCITIC LEUKEMIA: -BETA CELL RECEPTOR INHIBITOR: -B cell receptor inhibitor causes chronic lymphocytic leukemia remission
PCI-32765 applies molecularly aimed attack to disease usually treated with chemotherapy combinations SAN DIEGO - A new, targeted approach to treating chronic lymphocytic leukemia has produced ...
- HEMATO-ONCOLOGY: -UH Seidman Cancer Center researchers present at American Society of Hematology Annual Meeting
New research findings in 25 presentations CLEVELAND: Researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine ...
- RED CELLS / Study: transfusion not always best treatment for anemia, age of stored blood may play a role
LEXINGTON, Ky. (Oct. 11, 2011) — University of Kentucky researchers, including lead author Samy Selim of the Division of Cardiovascular Medicine and the Saha Cardiovascular Research Center, ...
- HEMATO: ONOLOGY: -Newly identified DNA repair defect linked to increased risk of leukemia relapse
St. Jude Children's Research Hospital scientists tie low levels of a key DNA repair protein to loss of regulatory genes in a study that offers new clues about why acute lymphoblastic leukemia ...
- GENE DEFECT & LEUKEMIA:- Gene defect that predisposes people to leukemia discovered
Those at risk because of family history may soon obtain tests to detect the genetic error before symptoms emerge IMAGE: Dr. Marshall S. Horwitz, professor of pathology at the University ...
- TARGETED MOLECULAR THERAPIES: -Progress in understanding the hemoglobin switch
During fetal development and the first 6 months of neonatal life, a complex pattern of globin gene expression occurs called the hemoglobin switch (Figure 1Figure 1 The Human β-like Globin ...
- HEMATO-ONCOLOGY & EPIDEMIOLOGY: -Growing up near livestock tied to blood cancers
THURSDAY, July 28 -Children raised on livestock farms are at significantly greater risk of developing blood cancers -- such as leukemia, multiple myeloma and non-Hodgkin's lymphoma -- ...
- HEMATO-ONCOLOGY: -Hodgkin's lymphoma — the great teacher
Over the past half century, the field of oncology has drawn valuable insights from the management of Hodgkin's lymphoma. One early lesson was that the primary treatment should be ...
- HEMATOLOGY: -The dawn of the molecular era of the myelodysplastic syndromes
The myelodysplastic syndromes are a heterogeneous group of clonal hematopoietic stem-cell diseases characterized by cytopenias, dysplasia in one or more of the myeloid cell lines, ineffective ...
