Annals ofHematology

Volume: 3 - Number: 14 - January 15, 2003

Outstanding

Finally, how myeloma lyses bone

Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortality

Receptor- and mitochondrial-mediated apoptosis in acute leukemia: a translational view

Chemokines

Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties

Transgenic overexpression of the CC chemokine CCL21 disrupts T-cell migration

Clinical and Therapeutics Observations

Busulfan plus cyclophosphamide compared with total-body irradiation plus cyclophosphamide before marrow transplantation for myeloid leukemia: long-term follow-up of 4 randomized studies

Comparison of idarubicin + ara-C-, fludarabine + ara-C-, and topotecan + ara-C-based regimens in treatment of newly diagnosed acute myeloid leukemia, refractory anemia with excess blasts in transformation, or refractory anemia with excess blasts

Decreased transfusion requirements for patients receiving nonmyeloablative compared with conventional peripheral blood stem cell transplants from HLA-identical siblings

Superior outcome of infant acute myeloid leukemia with intensive chemotherapy: results of the Japan Infant Leukemia Study Group

Nonablative allogeneic hematopoietic transplantation as adoptive immunotherapy for indolent lymphoma: low incidence of toxicity, acute graft-versus-host disease, and treatment-related mortality

Human recombinant factor IX: safety and efficacy studies in hemophilia B patients previously treated with plasma-derived factor IX concentrates

Focus

Long-term immune reconstitution after marrow transplantation

Plasmacytoid dendritic cells: ready to be tested in vivo

Finally, how myeloma lyses bone

Some signals are more equal than others

Gene Therapy

Effects of CD2 locus control region sequences on gene expression by retroviral and lentiviral vectors

Plenary Article

Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome

Isolation and characterization of plasmacytoid dendritic cells from Flt3 ligand and granulocyte-macrophage colony-stimulating factor-treated mice

Myeloma cells induce imbalance in the osteoprotegerin/osteoprotegerin ligand system in the human bone marrow environment

Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

Reviews

Receptor- and mitochondrial-mediated apoptosis in acute leukemia: a translational view