Annals ofHematology

Volume: 3 - Number: 15 - February 15, 2003

Outstanding

Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin

Structure-function analysis of the antioxidant properties of haptoglobin

A rheostatic mechanism for T-cell inhibition based on elevation of activation thresholds

The B-cell receptor of a hepatitis C virus (HCV)-associated non-Hodgkin lymphoma binds the viral E2 envelope protein, implicating HCV in lymphomagenesis

Hematopoiesis

Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors

Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin

Expression and function of CD105 during the onset of hematopoiesis from Flk1+ precursors

Transforming growth factor 1 mediates cell-cycle arrest of primitive hematopoietic cells independent of p21Cip1/Waf1 or p27Kip2

A cytoplasmic serine protein kinase binds and may regulate the Fanconi anemia protein FANCA

Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein mutant mice

The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors

Hemostasis, Thrombosis and Vascular Biology

Identification of CD146 as a component of the endothelial junction involved in the control of cell-cell cohesion

Congenital afibrinogenemia: mutations leading to premature termination codons in fibrinogen A-chain gene are not associated with the decay of the mutant mRNAs

Structure-function analysis of the antioxidant properties of haptoglobin

Regulatory role of tetraspanin CD9 in tumor-endothelial cell interaction during transendothelial invasion of melanoma cells

Immunobiology

A rheostatic mechanism for T-cell inhibition based on elevation of activation thresholds

The normal cellular prion protein is strongly expressed by myeloid dendritic cells

Asymptomatic primary Epstein-Barr virus infection occurs in the absence of blood T-cell repertoire perturbations despite high levels of systemic viral load

The B-cell receptor of a hepatitis C virus (HCV)-associated non-Hodgkin lymphoma binds the viral E2 envelope protein, implicating HCV in lymphomagenesis

Circulating blood dendritic cells from myeloid leukemia patients display quantitative and cytogenetic abnormalities as well as functional impairment

Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys

Neoplasia

Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1- and type 2-infected cells by a caspase-3-dependent mechanism involving Bcl-2 cleavage

Role of protein kinase C isoform in Fas resistance of immature myeloid KG1a leukemic cells

Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells

Phagocytes

High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes

Red Cells

Correction of cross-linker sensitivity of Fanconi anemia group F cells by CD33-mediated protein transfer

Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice

Cellular zinc content is a major determinant of iron chelator-induced apoptosis of thymocytes

Molecular basis of the adult i phenotype and the gene responsible for the expression of the human blood group I antigen