Annals ofHematology

Volume: 3 - Number: 21 - November 15, 2003

Outstanding

A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover

A common polymorphism in the annexin V Kozak sequence (1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients

Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa

Clonal lymphocytosis of uncertain significance (CLUS): what clues will CLUS yield?

Brief Reports

Anemia and iron overload due to compound heterozygosity for novel ceruloplasmin mutations

BCR-ABL point mutants isolated from patients with imatinib mesylate-resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 91

Chemokines

CCL19 induces rapid dendritic extension of murine dendritic cells

Clinical observations and therapeutic assays

A phase 2 study of imatinib in patients with relapsed or refractory Philadelphia chromosome-positive acute lymphoid leukemias

Bone marrow transplantation from HLA-identical siblings as treatment for myelodysplasia

Clinicobiological features and outcome of acute promyelocytic leukemia occurring as a second tumor: the GIMEMA experience

Comparison of T-cell-depleted and non-T-cell-depleted unrelated donor transplantation for hematologic diseases: clinical outcomes, quality of life, and costs

Hematopoiesis

A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover

Adhesion of synchronized human hematopoietic progenitor cells to fibronectin and vascular cell adhesion molecule-1 fluctuates reversibly during cell cycle transit in ex vivo culture

Hemostasis, Thrombosis and Vascular Biology

A common polymorphism in the annexin V Kozak sequence (1C>T) increases translation efficiency and plasma levels of annexin V, and decreases the risk of myocardial infarction in young patients

Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa

Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome

Biphasic transmittance waveform in the APTT coagulation assay is due to the formation of a Ca++-dependent complex of C-reactive protein with very-low-density lipoprotein and is a novel marker of impending disseminated intravascular coagulation

Immunobiology

A prospective study on the evolution of the T-cell repertoire in patients with Sézary syndrome treated by extracorporeal photopheresis

CD8 T-cell responses to Wilms tumor gene product WT1 and proteinase 3 in patients with acute myeloid leukemia

Creating space: an antigen-independent, CpG-induced peripheral expansion of naive and memory T lymphocytes in a full T-cell compartment

Into the blood

Clonal lymphocytosis of uncertain significance (CLUS): what clues will CLUS yield?

Neoplasia

2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells

A molecular compendium of genes expressed in multiple myeloma

Aberrant DNA methylation of p57KIP2 gene in the promoter region in lymphoid malignancies of B-cell phenotype

Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival

Characterization of hyaluronan synthase expression and hyaluronan synthesis in bone marrow mesenchymal progenitor cells: predominant expression of HAS1 mRNA and up-regulated hyaluronan synthesis in bone marrow cells derived from multiple myeloma patients

Constitutive expression of SOCS3 confers resistance to IFN- in chronic myelogenous leukemia cells

Reviews

Current molecular models for NADPH oxidase regulation by Rac GTPase

Transplantation

Aberrant regulation of superantigen responses during T-cell reconstitution and graft-versus-host disease in immunodeficient mice