Annals ofHematology

Volume: 4 - Number: 23 - January 15, 2004

Outstanding

Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva

High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients

Immunophenotypic clustering of myelodysplastic syndromes

Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion

Brief Reports

Human leukocyte antigens class II and tumor necrosis factor genetic polymorphisms are independent predictors of non-Hodgkin lymphoma outcome

Clinical observations and therapeutic assays

High incidence of human herpesvirus 6 infection with a high viral load in cord blood stem cell transplant recipients

Immunophenotypic clustering of myelodysplastic syndromes

Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse

Gene Therapy

Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors

Gene transfer improves erythroid development in ribosomal protein S19-deficient Diamond-Blackfan anemia

Graft-versus-leukemia effect after suicide-gene-mediated control of graft-versus-host disease

In vitro phenotypic correction of hematopoietic progenitors from Fanconi anemia group A knockout mice

Hematopoiesis

Human CD34+CXCR4 sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation

Hemostasis, Thrombosis and Vascular Biology

Hemin induces neuroglobin expression in neural cells

Heparin acts synergistically with interleukin-11 to induce STAT3 activation and in vitro osteoclast formation

Efficacy and Safety of Low-Dose Aspirin in Polycythemia Vera

Daily Aspirin — Only Half the Answer

Immunobiology

gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4+ lymphocytes

Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell-induced apoptosis

Human fetuses are able to mount an adultlike CD8 T-cell response

Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX

Into the blood

Gfi-1B and erythroid development

Neoplasia

Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog

Original plenary

Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion

Perspectives

A New Insight into the Formation of Osteolytic Lesions in Multiple Myeloma

Phagocytes

Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis

Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells

Red Cells

Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells

Solving Clinical Problems

True, True, and Related

Transfusional medicine

Frequency and load of hepatitis B virus DNA in first-time blood donors with antibodies to hepatitis B core antigen

Transplantation

High-level allogeneic chimerism achieved by prenatal tolerance induction and postnatal nonmyeloablative bone marrow transplantation

Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens

Interleukin 7 worsens graft-versus-host disease