Annals ofHematology

Volume: 6 - Number: 47 - February 15, 2006

Outstanding

Gene expression profiling of pediatric acute myelogenous leukemia

Antioxidative stress–associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress

glycoprotein I–dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

Gene Therapy

Tumor cells escape suicide gene therapy by genetic and epigenetic instability

Hematopoiesis

A GTPase-activating protein binds STAT3 and is required for IL-6–induced STAT3 activation and for differentiation of a leukemic cell line

The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1-deficient embryonic para-aortic splanchnopleural (P-Sp) region

Haploinsufficiency of AML1 results in a decrease in the number of LTR-HSCs while simultaneously inducing an increase in more mature progenitors

Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction

Increased and pathologic emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1low mice

Hemostasis, Thrombosis and Vascular Biology

Antioxidative stress–associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress

glycoprotein I–dependent lupus anticoagulant highly correlates with thrombosis in the antiphospholipid syndrome

The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage

Regulation of platelet membrane levels of glycoprotein VI by a platelet-derived metalloproteinase

Expression and analysis of a split premature termination codon in FGG responsible for congenital afibrinogenemia: escape from RNA surveillance mechanisms in transfected cells

Inhibition of thrombin generation by protein S at low procoagulant stimuli: implications for maintenance of the hemostatic balance

A shortened activated partial thromboplastin time is associated with the risk of venous thromboembolism

Stimulation of endothelial cell proliferation by FGF-2 in the presence of fibrinogen requires 3

Brief report RNAi-mediated silencing of CD40 prevents leukocyte adhesion on CD154-activated endothelial cells

Immunobiology

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

RelB regulates human dendritic cell subset development by promoting monocyte intermediates

Imprint of human cytomegalovirus infection on the NK cell receptor repertoire

Neoplasia

Gene expression profiling of pediatric acute myelogenous leukemia

Cytotoxic activity of the maytansinoid immunoconjugate B-B4–DM1 against CD138+ multiple myeloma cells