Clínical trials and olbservations
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)
Hematopoiesis
Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: results of a long-term survey
Hemostasis, thrombosis, and vascular biology
Homocysteine lowering by B vitamins and the secondary prevention of deep vein thrombosis and pulmonary embolism: a randomized, placebo-controlled, double-blind trial
Immunology
Human galectin-1, -2, and -4 induce surface exposure of phosphatidylserine in activated human neutrophils but not in activated T cells
Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB
IgA Fc receptor I signals apoptosis through the FcR ITAM and affects tumor growth
IL-15 and dermal fibroblasts induce proliferation of natural regulatory T cells isolated from human skin
Immune competence of cancer-reactive T cells generated de novo in adult tumor-bearing mice
Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
Into the blood
IVIg in ITP: no role for cytokines?
JAK2V617F and phenotype: questions galore
Monogamy and polygamy in T-cell receptor (TCR) chain association
Neoplasia
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas
INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity
JAK2V617F: prevalence in a large Chinese hospital population
Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness
Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus
Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: pathogenetic implications and clinical correlations
RED CELLS
Maturation and enucleation of primitive erythroblasts during mouse embryogenesis is accompanied by changes in cell-surface antigen expression
