Annals ofHematology

Volume: 10 - Number: 95 - February 14, 2010

Outstanding

Primary cystic lung light chain deposition disease: a clinicopathologic entity derived from unmutated B cells with a stereotyped IGHV4-34/IGKV1 receptor

Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-4

Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation

Genomic complexity in chronic lymphocytic leukemia

Immunobiology

Targeting a single mismatched minor histocompatibility antigen with tumor-restricted expression eradicates human solid tumors

Into the blood

GASing up iron delivery via STAT5

Genomic complexity in chronic lymphocytic leukemia

Neoplasia

Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia

HDAC6 inhibition enhances 17-AAG–mediated abrogation of hsp90 chaperone function in human leukemia cells

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

Primary cystic lung light chain deposition disease: a clinicopathologic entity derived from unmutated B cells with a stereotyped IGHV4-34/IGKV1 receptor

Relative value of ZAP-70, CD38, and immunoglobulin mutation status in predicting aggressive disease in chronic lymphocytic leukemia

Sµ mutation patterns suggest different progression pathways in follicular lymphoma: early direct or late from FL progenitor cells

Transcriptional repression of c-Myb and GATA-2 is involved in the biologic effects of C/EBP in p210BCR/ABL-expressing cells

Phagocytes

Granulocyte colony-stimulating factor delays neutrophil apoptosis by inhibition of calpains upstream of caspase-4

Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow

Toll-like receptor–mediated activation of neutrophils by influenza A virus

RED CELLS

Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression

HES1 is a novel interactor of the Fanconi anemia core complex

Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype

Transplantation

Graft-versus-host disease causes failure of donor hematopoiesis and lymphopoiesis in interferon- receptor-deficient hosts

In vivo–activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease

Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway