Annals ofHIV - Aids

Volume: 4 - Number: 36 - December 15, 2005

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BASIC SCIENCE

Assessment of longitudinal changes in HIV-specific effector activity in subjects undergoing untreated primary HIV infection.

Interleukin-2 therapy restores CD8 cell non-cytotoxic anti-HIV responses in primary infection subjects receiving HAART.

T-cell function after interleukin-2 therapy in HIV-infected patients is correlated with serum cortisol concentrations

Levels and patterns of neutrophil cell counts over the first 8 years of life in children of HIV-1-infected mothers.

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CLINICAL SCIENCE

Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.

Immunologic and clinical responses to highly active antiretroviral therapy over 50 years of age. Results from the French Hospital Database on HIV.

Survival in patients with HIV infection and viral hepatitis B or C: a cohort study.

Long-term safety of discontinuation of secondary prophylaxis against Pneumocystis pneumonia: Prospective multicentre study.

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Editorial Commentary

How effective is HAART in HCV and HIV coinfection?

Prospects for an AIDS vaccine: encourage innate immunity

Editorial reviews

The HIV Netherlands Australia Thailand research collaboration: lessons from 7 years of clinical research.

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EPIDEMIOLOGY & SOCIAL

The impact of attending a behavioural intervention on HIV incidence in Masaka, Uganda.

Cost-effectiveness of HIV postexposure prophylaxis following sexual or injection drug exposure in 96 metropolitan areas in the United States.

Syphilis increases HIV viral load and decreases CD4 cell counts in HIV-infected patients with new syphilis infections.

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Research letters

HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis.

IL-7 and Flt-3L plasma levels are increased during highly active antiretroviral therapy-associated IL-2 therapy.

Predictors of selection of K65R: tenofovir use and lack of thymidine analogue mutations.

Heterosexual transmission of multiple highly conserved viral variants in HIV-1 subtype C-infected seronegative women.

Tetanus vaccination with IL-2 during highly active antiretroviral therapy induces sustained and pronounced specific CD4 T-cell responses.

HIV viral shedding in semen: lack of correlation with systemic virus-specific CD8 responses.

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