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Antiviral`s agents

Preclinical Evaluation of GS-9160, a Novel Inhibitor of Human Immunodeficiency Virus Type 1 Integrase

Robust Antiviral Efficacy upon Administration of a Nucleoside Analog to Hepatitis C Virus-Infected Chimpanzees

SC29EK, a Peptide Fusion Inhibitor with Enhanced -Helicity, Inhibits Replication of Human Immunodeficiency Virus Type 1 Mutants Resistant to Enfuvirtide

Virologic Failure in First-Line Human Immunodeficiency Virus Therapy with a CCR5 Entry Inhibitor, Aplaviroc, plus a Fixed-Dose Combination of Lamivudine-Zidovudine: Nucleoside Reverse Transcriptase Inhibitor Resistance Regardless of Envelope Tropism

Virologic Failure in Therapy-Naïve Subjects on Aplaviroc plus Lopinavir-Ritonavir: Detection of Aplaviroc Resistance Requires Clonal Analysis of Envelope

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Clinical therapeutics

Prevalence and Risk Factors for Selection of Quinolone-Resistant Escherichia coli Strains in Fecal Flora of Patients Receiving Quinolone Therapy

Experimental Therapeutics

Pharmacodynamics of Tigecycline against Phenotypically Diverse Staphylococcus aureus Isolates in a Murine Thigh Model

Mechanisms of Action

Oritavancin Kills Stationary-Phase and Biofilm Staphylococcus aureus Cells In Vitro

Praziquantel Affects the Regulatory Myosin Light Chain of Schistosoma mansoni

Selectivity of TMC207 towards Mycobacterial ATP Synthase Compared with That towards the Eukaryotic Homologue

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Microbial susceptibility

Oral and Parenteral Therapeutic Options for Outpatient Urinary Infections Caused by Enterobacteriaceae Producing CTX-M Extended-Spectrum ?-Lactamases

Postantibiotic Effects of Telavancin against 16 Gram-Positive Organisms

Pharmacology

Pharmacokinetics and Absorption of Posaconazole Oral Suspension under Various Gastric Conditions in Healthy Volunteers

Pharmacokinetics and Safety of Caspofungin in Neonates and Infants Less than 3 Months of Age

Pharmacokinetics of High-Dose Oseltamivir in Healthy Volunteers

Population Pharmacokinetic Analysis of Ceftobiprole for Treatment of Complicated Skin and Skin Structure Infections

Population Pharmacokinetic Analysis of Voriconazole Plasma Concentration Data from Pediatric Studies

Population Pharmacokinetics of Emtricitabine in Human Immunodeficiency Virus Type 1-Infected Pregnant Women and Their Neonates

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Resistence mechanism

Plasmids Imparting Sulfonamide Resistance in Escherichia coli: Implications for Persistence

Quinolone Resistance in Neisseria gonorrhoeae: Rapid Genotyping of Quinolone Resistance-Determining Regions in gyrA and parC Genes by Melting Curve Analysis Predicts Susceptibility

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