Annals ofClinical Investigation

Volume: 2 - Number: 6 - March 1, 2002

Outstanding

Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity

Arsenic inhibition of telomerase transcription leads to genetic instability

Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy

STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia

Cell and Molecular Physiology

p38 MAP kinase modulates liver cell volume through inhibition of membrane Na+ permeability

PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy

Commentaries

Turning down insulin signaling

Out, damned dot: studies of the NAD(P)H oxidase in atherosclerosis

Development and Cancer

Arsenic inhibition of telomerase transcription leads to genetic instability

Infection and Immunity

X-deficient woodchuck hepatitis virus mutants behave like attenuated viruses and induce protective immunity in vivo

STAT4 and STAT6 regulate systemic inflammation and protect against lethal endotoxemia

Molecular and Genetic Medicine

Expression of the endoplasmic reticulum molecular chaperone (ORP150) rescues hippocampal neurons from glutamate toxicity

Perspectives

Is the class A macrophage scavenger receptor (SR-A) multifunctional? - The mouse\'s tale

Series Introduction: Multiligand receptors and human disease

The experimental use of antisense oligonucleotides: a guide for the perplexed

DNA vaccination places tumors in double jeopardy

Autoantibodies as predictors of disease

Autoantibodies as reporters identifying aberrant cellular mechanisms in tumorigenesis

John Ashkenas

Vascular Biology and Thrombosis

p47phox is required for atherosclerotic lesion progression in ApoEagment-->p47phox is required for atherosclerotic lesion progression in ApoE–/– mice

Exacerbated vein graft arteriosclerosis in protein kinase Co-ull mice

Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation

Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity