Annals ofClinical Investigation

Volume: 2 - Number: 15 - December 1, 2002

Outstanding

Increased ABCA1 activity protects against atherosclerosis

Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

The choreography of cyclooxygenases in the kidney

Strategies for an HIV vaccine

Articles

Enhanced ERK-1/2 activation in mice susceptible to coxsackievirus-induced myocarditis

Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent

Myeloerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S

APRIL modulates B and T cell immunity

Identification of a biochemical link between energy intake and energy expenditure

Lifetime exposure to a soluble TGF-ß antagonist protects mice against metastasis without adverse side effects

Biotin dependency due to a defect in biotin transport

Estrogen alters thresholds for B cell apoptosis and activation

Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis

Increased ABCA1 activity protects against atherosclerosis

Glucagon-like peptide-1 receptor stimulation increases blood pressure and heart rate and activates autonomic regulatory neurons

Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome

Opposite effects of cyclooxygenase-1 and -2 activity on the pressor response to angiotensin II

Immune complex–mediated antigen presentation induces tumor immunity

Commentaries

Human CYP7A1 deficiency: progress and enigmas

The choreography of cyclooxygenases in the kidney

Focus

The therapeutic potential of modulating the ceramide/sphingomyelin pathway

Perspectives

Influenza vaccines: present and future

Strategies for an HIV vaccine

Live-attenuated virus vaccines for respiratory syncytial and parainfluenza viruses: applications of reverse genetics