Annals ofClinical Investigation

Volume: 3 - Number: 24 - December 15, 2003

Outstanding

Leaky "Feet" and Sudden Death

Hypoxia, BNip3 Proteins, and the Mitochondrial Death Pathway in Cardiomyocytes

Withdrawal of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Elicits Oxidative Stress and Induces Endothelial Dysfunction in Mice

Transcriptional Control of Cardiac Allograft Vasculopathy by Early Growth Response Gene-1 (Egr-1)

Cellular Biology

Comparison of Sphingosine 1-Phosphate–Induced Intracellular Signaling Pathways in Vascular Smooth Muscles: Differential Role in Vasoconstriction

Inducible Expression of BNIP3 Provokes Mitochondrial Defects and Hypoxia-Mediated Cell Death of Ventricular Myocytes

Editorial

New Roads Leading to Ca2+ Sensitization

Connexin Diversity: Discriminating the Message

Embryogenesis of Transposition of the Great Arteries: A Lesson From the Heart

Leaky "Feet" and Sudden Death

Hypoxia, BNip3 Proteins, and the Mitochondrial Death Pathway in Cardiomyocytes

Integrative Physiology

Withdrawal of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Elicits Oxidative Stress and Induces Endothelial Dysfunction in Mice

Aldose Reductase Is an Obligatory Mediator of the Late Phase of Ischemic Preconditioning

Inactivation of Enhanced Expression of Gi Proteins by Pertussis Toxin Attenuates the Development of High Blood Pressure in Spontaneously Hypertensive Rats

Cardiac Dysfunction in Hypertrophic Cardiomyopathy Mutant Tropomyosin Mice Is Transgene-Dependent, Hypertrophy-Independent, and Improved by ß-Blockade

Molecular Medicine

Cardiac Gap Junction Channels Show Quantitative Differences in Selectivity

Sphingosylphosphorylcholine Is a Novel Messenger for Rho-Kinase–Mediated Ca2+ Sensitization in the Bovine Cerebral Artery: Unimportant Role for Protein Kinase C

Identification of 5-Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice

Intrauterine Growth Retardation Is Associated With Reduced Activity and Expression of the Cationic Amino Acid Transport Systems y+/hCAT-1 and y+/hCAT-2B and Lower Activity of Nitric Oxide Synthase in Human Umbilical Vein Endothelial Cells

Transcriptional Control of Cardiac Allograft Vasculopathy by Early Growth Response Gene-1 (Egr-1)

3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Interfere With Angiogenesis by Inhibiting the Geranylgeranylation of RhoA

Cyclophilin-Mediated Pathways in the Effect of Cyclosporin A on Endothelial Cells: Role of Vascular Endothelial Growth Factor

Intimal Smooth Muscle Cells as a Target for Peroxisome Proliferator-Activated Receptor- Ligand Therapy

Enhanced Basal Activity of a Cardiac Ca2+ Release Channel (Ryanodine Receptor) Mutant Associated With Ventricular Tachycardia and Sudden Death

Report

Knockout Mice for Pharmacological Screening: Testing the Specificity of Na+-Ca2+ Exchange Inhibitors

Reviews

Cardiac Septation: A Late Contribution of the Embryonic Primary Myocardium to Heart Morphogenesis

Differentiation of Pluripotent Embryonic Stem Cells Into Cardiomyocytes