Annals ofClinical Investigation

Volume: 7 - Number: 60 - January 15, 2007

Outstanding

Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues

Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion

Mutation of ß-glucosidase 2 causes glycolipid storage disease and impaired male fertility

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

Commentaries

Imaging tumor angiogenesis

Microglia: a cellular vehicle for CNS gene therapy

Myeloid suppressor cells regulate the adaptive immune response to cancer

Pili prove pertinent to enterococcal endocarditis

Investigational Article

Hyperactivation of p21ras and PI3K cooperate to alter murine and human neurofibromatosis type 1–haploinsufficient osteoclast functions

Impaired regulation of NF-B and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism

Interaction of mature CD3+CD4+ T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid

Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues

Local application of FTY720 to the lung abrogates experimental asthma by altering dendritic cell function

Mast cell CD30 ligand is upregulated in cutaneous inflammation and mediates degranulation-independent chemokine secretion

Mll partial tandem duplication induces aberrant Hox expression in vivo via specific epigenetic alterations

Muscular atrophy of caveolin-3–deficient mice is rescued by myostatin inhibition

Mutation of ß-glucosidase 2 causes glycolipid storage disease and impaired male fertility

NF-B regulation of endothelial cell function during LPS-induced toxemia and cancer

NF-B2 is required for the establishment of central tolerance through an Aire-dependent pathway

PLC2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB3

Rai1 duplication causes physical and behavioral phenotypes in a mouse model of dup(17)(p11.2p11.2)

Rapid vascular regrowth in tumors after reversal of VEGF inhibition

Science in Medicine

Myasthenia gravis: past, present, and future