Annals ofClinical Investigation

Volume: 7 - Number: 63 - April 15, 2007

Outstanding

Heme oxygenase–1 and carbon monoxide suppress autoimmune neuroinflammation

Dependence of intestinal granuloma formation on unique myeloid DC-like cells

Autoantibody selection and production in early human life

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

Commentaries

Autoantibody selection and production in early human life

CHIP-ping away at tau

Editorial

A new JCI conflict-of-interest policy

Evolution, not revolution

Investigational Article

The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T–mediated virulence

Mechanism underlying inhibition of intestinal apical Cl–/OH– exchange following infection with enteropathogenic E. coli

Heme oxygenase–1 and carbon monoxide suppress autoimmune neuroinflammation

The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage

Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

Inhaled iloprost suppresses the cardinal features of asthma via inhibition of airway dendritic cell function

Primitive hematopoietic cells resist HIV-1 infection via p21Waf1/Cip1/Sdi1

A proximal activator of transcription in epithelial-mesenchymal transition

Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8+ T cells

Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8

Aldosterone-induced Sgk1 relieves Dot1a-Af9–mediated transcriptional repression of epithelial Na+ channel

Antiinflammatory adaptation to hypoxia through adenosine-mediated cullin-1 deneddylation

Dependence of intestinal granuloma formation on unique myeloid DC-like cells

Gene expression analysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets

Reviews

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

ECM remodeling in hypertensive heart disease

Fibrosis and diseases of the eye