Annals ofClinical Investigation

Volume: 8 - Number: 73 - February 15, 2008

Outstanding

Blocking TNF-? in mice reduces colorectal carcinogenesis associated with chronic colitis

Bone building with bortezomib

Can you hear me now? A genetic model of otitis media with effusion

Cholesterol in islet dysfunction and type 2 diabetes

Commentaries

A skewed view of X chromosome inactivation

Anticonvulsant effects of leptin in epilepsy

Antimalarial therapy prevents Myc-induced lymphoma

Blood is thicker than lymph

Bone building with bortezomib

Can you hear me now? A genetic model of otitis media with effusion

Colitis and cancer: a tale of inflammatory cells and their cytokines

Investigational Article

A shed form of LDL receptor–related protein–1 regulates peripheral nerve injury and neuropathic pain in rodents

Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia

Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice

Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

Adrenomedullin signaling is necessary for murine lymphatic vascular development

AMP-activated protein kinase regulates CO2-induced alveolar epithelial dysfunction in rats and human cells by promoting Na,K-ATPase endocytosis

Blocking TNF-? in mice reduces colorectal carcinogenesis associated with chronic colitis

Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex

Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells

Review

A calculated response: control of inflammation by the innate immune system

Building bone to reverse osteoporosis and repair fractures

Science in Medicine

Antipsychotics in the treatment of autism

Cholesterol in islet dysfunction and type 2 diabetes