Annals ofClinical Investigation

Volume: 8 - Number: 75 - April 15, 2008

Outstanding

Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice

Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice

Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP

Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1

Commentaries

Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1

Investigational Article

Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice

Multipotent adult progenitor cells sustain function of ischemic limbs in mice

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis

Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice

No evidence that skewing of X chromosome inactivation patterns is transmitted to offspring in humans

Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease

Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP

Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site

Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice

Phospholipase C ?3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice

Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells

PPAR? activation is essential for HCV core protein–induced hepatic steatosis and hepatocellular carcinoma in mice

Role of Gas6 in erythropoiesis and anemia in mice

Notice

Rewarding the fruits of young labor

Personal Perspective

Molecular pathogenesis of emphysema

Review

Making a bad thing worse: adverse effects of stress on drug addiction

Molecular targets for tendon neoformation

Physiological systems under pressure

Technical's Advances

Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice