
Increasing evidence of lipid peroxidation in food deterioration and pathophysiology of diseases have revealed the need for a pure lipid hydroperoxide (LOOH) reference as an authentic standard for ...
In an effort to discover new mouse models of cardiovascular disease using ENU mutagenesis followed by high-throughput phenotyping, we have identified a new mouse mutation, C699Y, in the LDL receptor ...
Eight proteins potentially involved in cholesterol efflux (ABCA1, ABCG1, CYP27A1, phospholipid transfer protein (PLTP), SR-B1, caveolin-1, cholesteryl ester transfer protein (CETP) and apolipoprotein ...
Both a low-carbohydrate diet or a Mediterranean-style diet may be "effective alternatives" to a low-fat diet, with more favorable effects on lipids and/or glycemic control, new research suggests1. ...
The novel combination of niacin and laropiprant (Tredaptive, Merck) is now approved in the European Union, as well as Iceland and Norway, and is available for use in patients with dyslipidemia and ...
Prostaglandins Leukot Essent Fatty Acids 2008; 78: 327-335 Reduction in triglycerides in healthy middle-aged men as a result of fish oil supplementation is influenced by their CD36 genotype, report ...
Mayo Clin Proc 2008; 83: 758-764 A combination of red yeast rice and fish oil supplementation as well as lifestyle changes lowers low-density lipoprotein (LDL) cholesterol by similar ...
Am J Clin Nutr 2008; 88: 216-223 Elevated blood plasma levels of eicosapentaenoic acid (EPA) and docosapentaenoic acid (DPA) are associated with reduced risk for nonfatal myocardial infarction (MI) ...
A small but intriguing clinical trial has shown that atorvastatin (Lipitor, Pfizer) was no more effective than placebo in slowing the progression of atherosclerosis1. Over the course of the 12-month ...
The American Academy of Pediatrics has issued a new clinical report on lipid screening and cardiovascular health in children1, a report that has taken on new urgency given the epidemic of childhood ...
The utility of Lp(a) in predicting the future risk of heart disease is markedly attenuated among women taking hormone therapy, a new study suggests1. The study, published online July 1, 2008 in the ...
Objectives: This study assesses whether the relationship of lipoprotein(a) [Lp(a)] with cardiovascular risk may be modified by concurrent hormone replacement therapy (HT). Background: Prior ...
Neutral Cholesteryl ester hydrolase (CEH) mediated hydrolysis of cellular cholesteryl esters (CE) is required not only to generate free cholesterol for efflux from macrophages but also to release FC ...
Stearoyl-CoA desaturase 1 (SCD1) catalyzes conversion of stearate (18:0) to oleate (18:1n-9), and palmitate (16:0) to palmitoleate (16:1), which are key steps in triglyceride synthesis in the fatty ...
In addition to hepatic expression, cholesteryl ester transfer protein (CETP) and hepatic lipase (HL) are expressed by human macrophages. The combined actions of these proteins have profound effects ...