Annals of Lipids in Biology & Medicine
Issue 69, February 14, 2010
Additional content
News
- FULLTEXT: -LIPIDS: -The association between serum levels of oxLDL-lgG and oxLDL-lgM autoantibody with adult acute myeloblastic leukaemia
Abstract & Aim To evaluate the relationship between serum antibodies against ox-LDL levels and adult acute myeloblastic leukemia (AML). Methods Forty three patients with AML ...
- FULLTEXT: -LIPIDS: -Method for determining arachidonic:eicosapentaenoic acid ratios in whole blood lipids: correlation with erythrocyte membrane ratios and validation in a large Italian population of various ages and pathologies
Abstract & Background Omega-3 and -6 polyunsaturated fatty acids (LCPUFA), are important for good health conditions. hey are present in membrane phospholipids. The ratio of total n-6:n-3 LCPUFA ...
- FULLTEXT: -LIPIDS: -Elucidation of the effects of a high fat diet on trace elements in rabbit tissues using atomic absorption spectroscopy
Abstract Background The mechanism of atherogenesis is not yet fully understood despite intense study in this area. The effects of high fat diet (HFD) on the changes of trace elements [iron (Fe), ...
- FULTEXT: -LIPIDS: -Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice
Abstract Ceramide kinase (CERK) produces the bioactive lipid ceramide-1-phosphate (C1P) and is a key regulator of ceramide and dihydroceramide levels. It is likely that CERK and C1P play a role in ...
- LIPIDS: -Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages
Objective Reconstituted high-density lipoprotein (rHDL) is of interest as a potential novel therapy for atherosclerosis because of its ability to promote free cholesterol (FC) mobilization after ...
- LIPIDS: -Regular exercise training prevents aortic valve disease in low-density lipoprotein–receptor–deficient mice
Background Regular exercise training (ET) slows the progression of atherosclerotic lesions, reduces oxidative stress, and increases nitric oxide bioavailability, all of which may be expected to ...
- LIPIDS: -Association of statin prescription with small abdominal aortic aneurysm progression
Background Statins have been suggested to reduce expansion of abdominal aortic aneurysms (AAAs) independent of lipid-lowering effects.Methods We assessed the association of statin treatment and ...
- LIPIDS: -The National Niemann-Pick Type C1 Disease Database: correlation of lipid profiles, mutations, and biochemical phenotypes
Niemann-Pick type C1 disease (NPC1) is an autosomal recessive lysosomal storage disorder characterized by neonatal jaundice, hepatosplenomegaly, and progressive neurodegeneration. The present study ...
- FULLTEXT: -LIPIDS: -Assessing the efficacy of protein farnesyltransferase inhibitors in mouse models of progeria
Hutchinson-Gilford progeria syndrome (HGPS) is caused by the accumulation of a farnesylated form of prelamin A (progerin). Previously, we showed that blocking protein farnesylation with a ...
- LIPIDS: -Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung
Vitamin A (VA) is essential for fetal lung development and postnatal lung maturation. VA is stored mainly as retinyl esters (REs), which may be mobilized for production of retinoic acid (RA). This ...
- LIPIDS: -Prevention of high-fat diet-induced muscular lipid accumulation in rats by lipoic acid is not mediated by AMPK activation[S]
Skeletal muscle triglyceride accumulation is associated with insulin resistance in obesity. Recently, it has been suggested that lipoic acid (ALA) improves insulin sensitivity by lowering ...
- LIPIDS & VORICONAZOL & BRAIN CHOLESTEROL: -The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo
Cholesterol 24S-hydroxylase (CYP46A1) is of key importance for cholesterol homeostasis in the brain. This enzyme seems to be resistant toward most regulatory factors and at present no drug effects on ...
- LIPIDS: -New cholesterol-specific antibodies remodel HIV-1 target cells’ surface and inhibit their in vitro virus production
The importance of membrane rafts in HIV-1 infection is still in the focus of interest. Here, we report that new monoclonal anticholesterol IgG antibodies (ACHAs), recognizing clustered membrane ...
- LIPIDS: -Rapid quantification of conjugated and unconjugated bile acids and C27 precursors in dried blood spots and small volumes of serum
The aim of the study was to develop a method for fast und reliable diagnosis of peroxisomal diseases and to facilitate differential diagnosis of cholestatic hepatopathy. For the quantification of ...
- LIPIDS: -Enzymatic assessment of cholesterol on electrophoresis gels for estimating HDL size distribution and plasma concentrations of HDL subclasses
Background. The aim of this study was to develop an enzymatic cholesterol staining method to determine HDL subclasses in a polyacrylamide gradient gel electrophoresis, which further allows staining ...
