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Arterial Hypertension

Candesartan Inhibits Carotid Intimal Thickening and Ameliorates Insulin Resistance in Balloon-Injured Diabetic Rats

Cardiac and Renal Effects of Growth Hormone in Volume Overload–Induced Heart Failure: Role of NO

Cardiac and Vascular Remodeling in Older Adults With Borderline Isolated Systolic Hypertension: The ICARe Dicomano Study

Cardiomyocyte Apoptotic Cell Death in Arterial Hypertension: Mechanisms and Potential Management

Cationic Amino Acid Transport in the Renal Medulla and Blood Pressure Regulation

Centrally Mediated Effects of Bromocriptine on Cardiac Sympathovagal Balance

Characterization of the Microglial Response to Cerebral Ischemia in the Stroke-Prone Spontaneously Hypertensive Rat

Chronic ACE Inhibition Enhances the Endothelial Control of Arterial Mechanics and Flow-Dependent Vasodilatation in Heart Failure

Comparative Effects of Ramipril on Ambulatory and Office Blood Pressures: A HOPE Substudy

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Autoimmunity

Cancer-associated neuromusculoskeletal syndromes Recognizing the rheumatic-neoplastic connection

Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

Cardiology

CD40 Signaling and Plaque Instability

Cerebrovascular Disease

Characteristics and Superoxide-Induced Activation of Reconstituted Myocardial Mitochondrial ATP-Sensitive Potassium Channels

Chronic Hypoxia Stimulates Periarterial Sympathetic Nerve Development in Chicken Embryo

Clinical and Echocardiographic Characteristics of Patients With Left Atrial Thrombus and Sinus Rhythm: Experience in 20 643 Consecutive Transesophageal Echocardiographic Examinations

Clinical and Genetic Heterogeneity of Right Bundle Branch Block and ST-Segment Elevation Syndrome : A Prospective Evaluation of 52 Families

Comparison of Novel Hemostatic Factors and Conventional Risk Factors for Prediction of Coronary Heart Disease

Congestive Heart Failure: Fifty Years of Progress

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Clinical Microbiology

Catheter-Related Microbacterium Bacteremia Identified by 16S rRNA Gene Sequencing

Characterization of an Unusual Mycobacterium: a Possible Missing Link between Mycobacterium marinum and Mycobacterium ulcerans

Characterization of Salmonella Serovars by PCR-Single-Strand Conformation Polymorphism Analysis

Comparison of an Industry-Derived LCx Chlamydia pneumoniae PCR Research Kit to In-House Assays Performed in Five Laboratories

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Clinical Psychiatric

Cannabis and health

Cerebral white matter lesions in bipolar affective disorder: relationship to outcome

Changes in the quality of life of patients receiving antidepressant medication in primary care: validation of the WHOQOL-100

Childhood Abuse and Psychiatric Disorders Among Single and Married Mothers

Chronic benzodiazepine use in general practice patients with depression: an evaluation of controlled treatment and taper-off: Report on behalf of the Dutch Chronic Benzodiazepine Working Group

Cognitive deficits in depression: Possible implications for functional neuropathology

Common mental disorders in Santiago, Chile: Prevalence and socio-demographic correlates

Community care for people with mental disorders in developing countries: Problems and possible solutions

Community study of depression in old age in Taiwan: Prevalence, life events and socio-demographic correlates

Comparison of the outcome and treatment of psychosis in people of Caribbean origin living in the UK and British Whites: Report from the UK700 trial

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Critical Care

Caudoputamen Is Damaged by Hypocapnia During Mechanical Ventilation in a Rat Model of Chronic Cerebral Hypoperfusion

Central Venous and Bladder Pressure Reflect Transdiaphragmatic Pressure During Pressure Support Ventilation

Cerebral Metabolic Abnormalities in COPD Patients Detected by Localized Proton Magnetic Resonance Spectroscopy

Changes in BP Induced by Passive Leg Raising Predict Response to Fluid Loading in Critically Ill Patients*

Changes in Intervention and Outcome in Elderly Patients With Subarachnoid Hemorrhage

Clinical Course and Outcome of Patients Admitted to an ICU for Status Asthmaticus

Clinicians’ Approaches to Mechanical Ventilation in Acute Lung Injury and ARDS

Comparison of Cardiac Output and Circulatory Blood Volumes by Transpulmonary Thermo-Dye Dilution and Transcutaneous Indocyanine Green Measurement in Critically Ill Patients

Noticias del dĂ­a

Diabetes

Case Study: Infections in Diabetes Mellitus

Case Study: The Recipe for Diabetes Success in the Hospital

Commitment to a Cure

Consensus Statements

Noticias del dĂ­a

Family Medicine

Cardiovascular Screening of Student Athletes

Caring for Caregivers

Cervical Spondylotic Myelopathy: A Common Cause of Spinal Cord Dysfunction in Older Persons

Clinical Briefs

Clinical Briefs

Clinical Briefs

Clinical Briefs

Clinical Briefs

Clinical Briefs

Clinical Briefs

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Geriatric Internal Medicine

Case 35-2001— An 81-Year-Old Man with Hypothermia, Bradycardia, and Confusion

Case 9-2002 — An 80-Year-Old Woman with Sudden Unilateral Blindness

CHOP Chemotherapy plus Rituximab Compared with CHOP Alone in Elderly Patients with Diffuse Large-B-Cell Lymphoma

Coeliac Disease in the ElderlyA Multicentre Italian Study

Comparison of Four Bioelectrical Impedance Analysis Formulas in Healthy Elderly Subjects

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Hematology

Case 16-2002 — A 41-Year-Old Woman with Global Headache and an Intracranial Mass

Case 19-2002 — A 13-Year-Old Girl with a Mass in the Left Parotid Gland and Regional Lymph Nodes

Case 27-2001— A 50-Year-Old Man with Marked Splenomegaly and Anemia

Case 29-2002 — A 17-Year-Old Boy with Acute Mitral Regurgitation and Pulmonary Edema

Case 6-2002— A 54-Year-Old Woman with Left, Then Right, Central-Retinal-Vein Occlusion

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease

CD8+ dendritic cells originate from the CD8 dendritic cell subset by a maturation process involving CD8, DEC-205, and CD24 up-regulation

Comparison of 200 mg/m2 melphalan and 8 Gy total body irradiation plus 140 mg/m2 melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: final analysis of the Intergroupe Francop

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Image and Radiology

Captopril MR Renography in a Swine Model: Toward a Comprehensive Evaluation of Renal Arterial Stenosis

CARACTERĂŤSTICAS OPERATIVAS DE LA PERFUSION MIOCARDICA DE REPOSO EN LA EVALUACION DEL DOLOR TORACICO EN URGENCIAS.

CARACTERIZACION MORFOLOGICA DE LA MIOCARDIOPATIA HIPERTROFICA MEDIANTE SPECT MIOCARDICO DE PERFUSION. ANALISIS CUANTITATIVO.

Cardiac Imaging by Means of Electrocardiographically Gated Multisection Spiral CT: Initial Experience

Case 28: Proximal Interruption of the Right Pulmonary Artery

Case 29: Gastric Trichobezoar and Subphrenic Abscess

Case 32

Case 33

Cerebrotendinous Xanthomatosis: The Spectrum of Imaging Findings and the Correlation with Neuropathologic Findings

Changes in Calcaneal Trabecular Bone Structure after Heart Transplantation: An MR Imaging Study

Characterization of Indeterminate (Lipid-poor) Adrenal Masses: Use of Washout Characteristics at Contrast-enhanced CT

COMBINED INTRAVENOUS AND INTRA-ARTERIAL THROMBOLYSIS IN ACUTE CEREBRAL INFARCT

Combined Perfusion- and Diffusion-weighted MR Imaging in Acute Ischemic Stroke during the 1st Week: A Longitudinal Study

COMPARACION DEL CITRATO DE GaoLIO-67, DE LOS LEUCOCITOS MARCADOS CON EXAMETAZINA-TECNECIO-99M Y DE LA INMUNOGLOBULINA G MARCADA CON DTPA-INDIO-111 EN EL DIAGoNSTICO DE INFECCIONES-SEAS Y ARTICULARES.

Comparison of Doses for Bedside Examinations of the Chest with Conventional Screen-Film and Computed Radiography: Results of a Randomized Controlled Trial

Comprehensive MR Imaging of Acute Gynecologic Diseases

Computer-aided Design and Modeling of Workstations and Radiology Reading Rooms for the New Millennium

Noticias del dĂ­a

Immunoinfectology

Catalase, a Specific Antigen in the Feces of Human Subjects Infected with Helicobacter pylori

CD8+-T-Cell Response to Secreted and Nonsecreted Antigens Delivered by Recombinant Listeria monocytogenes during Secondary Infection

CD8-Deficient Mice Are Highly Susceptible to 5-Fluorouracil-Induced Lethality

Cell-Associated Interleukin-8 in Cord Blood of Term and Preterm Infants

Cellular Immune Responses to Recombinant Antigens in Pregnant Women Chronically Infected with Toxoplasma gondii

Central Importance of Immunoglobulin A in Host Defense against Giardia spp

Central Role for Interleukin-4 in Regulating Nitric Oxide-Mediated Inhibition of T-Cell Proliferation and Gamma Interferon Production in Schistosomiasis

Cervical Cat Scratch Disease Lymphadenitis in a Patient with Immunoglobulin M Antibodies to Toxoplasma gondii

Characterization of the Murine T-Lymphocyte Response to Salmonella enterica Serovar Typhimurium Infection

Chlamydia pneumoniae Secretion of a Protease-Like Activity Factor for Degrading Host Cell Transcription Factors Is Required for Major Histocompatibility Complex Antigen Expression

Cloning and Expression of a Helicobacter bilis Immunoreactive Protein

Comparative and Prospective Study of Different Immune Parameters in Healthy Subjects at Risk for Tuberculosis and in Tuberculosis Patients

Comparison of Murex Single-Use Diagnostic System with Traditional Enzyme Immunoassay for Detection of Exposure to Human Immunodeficiency Virus

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Infectology

CD4+ T Cell Kinetics and Activation in Human Immunodeficiency VirusInfected Patients Who Remain Viremic Despite Long-Term Treatment with Protease InhibitorBased Therapy

Characterization of the Antibody Response to Pneumococcal Glycoconjugates and the Effect of Heat-Labile Enterotoxin on IgG Subclasses after Intranasal Immunization

Children with hepatitis C

Clonal Relationships and Extended Virulence Genotypes among Escherichia coli Isolates from Women with a First or Recurrent Episode of Cystitis

Clones of Streptococcus pneumoniae Isolated from Nasopharyngeal Carriage and Invasive Disease in Young Children in Central Tennessee

Combined Interleukin-12 and Topical Chemotherapy for Established Leishmaniasis Drastically Reduces Tissue Parasitism and Relapses in Susceptible Mice

Complement Activation Induced by Purified Neisseria meningitidis Lipopolysaccharide (LPS), Outer Membrane Vesicles, Whole Bacteria, and an LPS-Free Mutant

Concordance between the CC Chemokine Receptor 5 Genetic Determinants That Alter Risks of Transmission and Disease Progression in Children Exposed Perinatally to Human Immunodeficiency Virus

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Internal Medicine

Cancer gene therapy using a survivin mutant adenovirus

CD4+CD28– costimulation-independent T cells in multiple sclerosis

Cellular-Telephone Use and Brain Tumors

Central Diabetes Insipidus in Children and Young Adults

Challenges to achieving clinical transplantation tolerance

Chemokines and atherosclerosis: what Adam Smith has to say about vascular disease

Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis

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Investigation

CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse

Cellular sensors of feast and famine

Cerebral gas embolism absorption during hyperbaric therapy: theory

Chronic tobacco smoke exposure increases airway sensitivity to capsaicin in awake guinea pigs

commentary

Computational modeling of RBC and neutrophil transit through the pulmonary capillaries

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Medical Bioethical

Canadians seek kidney transplants in poor countries

Cheating at medical school

Clinic sued for unauthorised use of sperm

Clinton outlaws genetic discrimination in federal jobs

Cloning of pigs bring xenotransplants closer

Closing the gap between professional teaching and practice

College inquiry clears hospital's cardiology services

Colombian newspaper delivers free cigarettes

Commons votes for human embryo stem cell research

Concerns about using and interpreting covert video surveillance • Commentary: Covert video surveillance is acceptable but only with a rigorous protocol

Confidentiality may be overvalued

Conjoined twins should be separated

Conjoined twins should be separated

Consent needed for organ retention, BMA says

Consultant suspended for not getting consent for cardiac procedure

Diabetes e Incretinas

Medical Physiology

Cardiac-Specific Overexpression of Inducible Nitric Oxide Synthase Does Not Result in Severe Cardiac Dysfunction

CCR4-bearing T cells participate in autoimmune diabetes

cGMP-Dependent Protein Kinase I Mediates the Negative Inotropic Effect of cGMP in the Murine Myocardium

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Nephrology

Case 15-2002 — A 53-Year-Old Man with a Myocardial Infarct and Thromboses after Coronary-Artery Bypass Grafting

Case 30-2001— A 22-Year-Old Man with Hyperthyroidism, Fever, Abdominal Pain, and Arthralgia

Case 31-2001— A 70-Year-Old Woman with End-Stage Renal Disease and Cutaneous Ulcers

Case 4-2002 — A 75-Year-Old Man with Acute Renal Failure Five Months after Cystoprostatectomy and Urethrectomy for Carcinoma

Cellular Injury Associated with Renal Thrombotic Microangiopathy in Human Immunodeficiency Virus–Infected Macaques

Cellular origin and hormonal regulation of K+-ATPase activities sensitive to Sch-28080 in rat collecting duct

Clinical Features and Outcomes in Children with Antineutrophil Cytoplasmic Autoantibody–Positive Glomerulonephritis Associated with Propylthiouracil Treatment

Comparison of Two Diets for the Prevention of Recurrent Stones in Idiopathic Hypercalciuria

Compensatory Renal Growth after Unilateral Nephrectomy in the Ovine Fetus

Concerted action of dopamine on renal and intestinal Na+-K+-ATPase in the rat remnant kidney

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Nutrition

Cardiovascular disease risk factors and diet of Fulani pastoralists of northern Nigeria

Carotene Alters the Morphology of NCI-H69 Small Cell Lung Cancer Cells

Characterization and Regulation of a Cloned Ovine Gastrointestinal Peptide Transporter (oPepT1) Expressed in a Mammalian Cell Line

Choline Deficiency–Induced Liver Damage Is Reversible in Pemt-/- Mice

Clinical characteristics and pharmacokinetics of purified soy isoflavones: single-dose administration to healthy men

Computer-assisted teaching of nutritional anemias and diabetes to first-year medical students

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Oncology

Cancer-associated Myofibroblasts Possess Various Factors to Promote Endometrial Tumor Progression

Carbonic Anhydrase (CA IX) Expression, a Potential New Intrinsic Marker of Hypoxia: Correlations with Tumor Oxygen Measurements and Prognosis in Locally Advanced Carcinoma of the Cervix

Case Report: Hand–Foot Syndrome Induced by the Oral Fluoropyrimidine S-2

Clinical and Molecular Responses in High-Grade Intraepithelial Neoplasia Treated with Topical Imiquimod 5%

Colon Cancer with Meningeal Carcinomatosis and Myelodysplastic Syndrome in a Patient Who Underwent Intensive Chemotherapy for Acute Myelogenous Leukemia: a Case Report

Comparison of Surgical Management of Thoracic Esophageal Carcinoma Between Two Referral Centers in Japan and China

Complete Atrio-ventricular Block as a Major Clinical Presentation of the Primary Cardiac Lymphoma: a Case Report

Constitutive Expression of Hypoxia-inducible Factor-1 Renders Pancreatic Cancer Cells Resistant to Apoptosis Induced by Hypoxia and Nutrient Deprivation

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Pathology

Cathepsin B Knockout Mice Are Resistant to Tumor Necrosis Factor--Mediated Hepatocyte Apoptosis and Liver Injury : Implications for Therapeutic Applications

CD36, a Class B Scavenger Receptor, Is Expressed on Microglia in Alzheimer’s Disease Brains and Can Mediate Production of Reactive Oxygen Species in Response to ß-Amyloid Fibrils

CD40-CD40 Ligand Disruption Does Not Prevent Hyperoxia-Induced Injury

Characterization of Prostate Cell Types by CD Cell Surface Molecules

Chemokine Ligand and Receptor Expression in the Pregnant Uterus : Reciprocal Patterns in Complementary Cell Subsets Suggest Functional Roles

Clinical Significance of Molecular Expression Profiles of Hürthle Cell Tumors of the Thyroid Gland Analyzed via Tissue Microarrays

Commensal-Associated Molecular Patterns Induce Selective Toll-Like Receptor-Trafficking from Apical Membrane to Cytoplasmic Compartments in Polarized Intestinal Epithelium

Composite Thymoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Involving the Anterior Mediastinum

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Pharmacology

Characterization of Rat Prepro-Orphanin FQ/Nociceptin(154-181): Nociceptive Processing in Supraspinal Sites

Pneumonology

Caregiver Strain Associated With Tracheostomy in Chronic Respiratory Failure

Rheumatology

Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis

Carpal Tunnel Syndrome

Case 18-2002 — A 48-Year-Old Man with a Cough and Bloody Sputum

Case 21-2002 — A 21-Year-Old Man with Arthritis during Treatment for Hyperthyroidism

Case 2-2003 — A 60-Year-Old Man with Mild Congestive Heart Failure of Uncertain Cause

Case 23-2002 — A 73-Year-Old Man with Leg Pains, Occipital Headaches, and Night Sweats

Case 30-2002 — An Eight-Year-Old Girl with Fever, Hemoptysis, and Pulmonary Consolidations

Case 39-2002 — A 35-Year-Old Man with Headache, Deviation of the Tongue, and Unusual Radiographic Abnormalities

Case 5-2003 — A 16-Year-Old Girl with a Rash and Chest Pain

Case 8-2002 — A 56-Year-Old Woman with a Persistent Left-Sided Pleural Effusion

Celecoxib versus Diclofenac and Omeprazole in Reducing the Risk of Recurrent Ulcer Bleeding in Patients with Arthritis

Circulating cytotoxic CD8+ CD28- T cells in ankylosing spondylitis

Combined antibiotic and free radical trap treatment is effective at combating Staphylococcus-aureus-induced septic arthritis

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Vascular Medicine

Cellular Redox State and Endothelial Dysfunction in Mildly Hyperhomocysteinemic Cystathionine ß-Synthase–Deficient Mice

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