Race does not appear to determine outcomes of patients with chronic kidney disease (CKD) undergoing percutaneous coronary intervention (PCI), say US researchers who report similar mortality and major ...

Ultrafiltration is effective for treating fluid overload, but there are no suitable machines for ambulatory treatment. This study summarizes the use of a light-weight wearable continuous ambulatory ...

Measuring both urinary albumin excretion (UAE) and estimated glomerular filtration rate (eGFR) could improve assessment of patients' cardiovascular (CV) risk related to kidney dysfunction, research ...

Calcium (Ca2+) and phosphate (Pi) are essential to many vital physiological processes. Consequently the maintenance of Ca2+ and Pi homeostasis is essential to a healthy existence. This occurs through ...

OBJECTIVE: To assess the preventive effect of the antioxidant N-acetylcysteine on postoperative acute renal failure in patients with renal insufficiency undergoing cardiac surgery. DESIGN: ...

Summary Magnesium ions are essential to all living cells. As the second most abundant intracellular cation, magnesium has a crucial role in fundamental metabolic processes such as DNA and protein ...

Abstract Delayed graft function (DGF) often occurs in kidney transplants from deceased donors. We wanted to provide studies giving more accurate non-invasive tests for acute rejection (AR). Using ...

CASE REPORT: JANUARY/29/ 2008A 31-year-old woman with bilateral nephrectomy due to bleeding angiomyolipomas from tuberous sclerosis received a kidney transplant with good early graft function. ...

Reduced renal function even in the normal to mildly impaired range is associated with an increased risk for coronary artery disease (CAD), a study in young, otherwise healthy men shows. "It seems ...

J Am Soc Nephrol 2007; advance online publication Patients with diabetes and chronic kidney disease (CKD) are at lower risk for cardiovascular (CV) events if they are treated with pioglitazone, ...

Background More frequent haemodialysis can improve both survival and quality of life of patients with chronic kidney disease. However, there is little capacity in the UK to allow patients to have ...

Abstract Telomerase and telomeres are attractive targets for anticancer therapy. This is supported by the fact that the majority of human cancers express the enzyme telomerase which is essential to ...

Abstract Hydrochlorothiazide (HCTZ) is used to manage hypertension and heart failure; however, its side effects include mild hypokalemia, metabolic abnormalities, and volume depletion, which might ...

Abstract & Objective. Estimation of glomerular filtration rate (eGFR) is essential in the diagnosis and monitoring of patients with kidney disease and for correct dosage of drugs eliminated from ...

Protein kinases catalyze the phosphorylation of serine/threonine or tyrosine residues, which may directly alter a protein’s functional properties. Kinases can also regulate protein functions ...