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- RESPIRATORY MEDICINE: High throughput evaluation of pulmonary surfactant adsorption and surface film formation
The assessment of new therapeutic strategies to cure surfactant associated lung disorders would greatly benefit from assay systems allowing routine evaluations of surfactant functions. We present a ...
- ALLERGY & IMMUNOLOGY: - Long-term bouts with hay fever worsen ability to breathe through your nose
New evidence for the first time suggests that people suffering from hay fever (allergic rhinitis) will over time experience a progressive worsening of their nasal passage functioning, depending on ...
- RESPIRATORY RESEARCH & VERSICAN : Versican may prevent elastic fiber repair in COPD
Respiratory Research 2008; 9: 41 27 May 2008 Elastic fiber repair processes in patients with chronic obstructive pulmonary disease (COPD) may be inhibited by elevated levels of versican, matrix ...
- ALVEOLAR MACROPHAGES (AMs): - From severe asthmatics are insensitive to corticosteroids
Thorax 2008:-27 May 2008 Alveolar macrophages (AMs) from patients with severe asthma demonstrate corticosteroid insensitivity, study findings indicate. The insensitivity is associated with increased ...
- ALLERGY & IMMUNOLOGY : - An insight into molecular mechanisms of human T helper cell differentiation
Abstract Selective activation of T helper (Th) cell subsets plays an important role in immune response to pathogens as well as in the pathogenesis of human allergy and inflammatory diseases. Th1 ...
- RESPIRATORY MEDICINE : - New treatment gives hope for pulmonary fibrosis patients
Patients with idiopathic pulmonary fibrosis (IPF) may have a new treatment option, according to researchers in Japan. In a Phase III, double-blind, placebo-controlled clinical trial, the ...
- ALLERGY & IMMUNOLOGY : - Farm moms may help children beat allergies
Mothers exposed to farms, particularly to barns and farm milk, while pregnant confer protection from allergies on their newborns, according to a group of German researchers, who will present their ...
- RESPIRATORY MEDICINE : - COPD patients benefit more from pulmonary rehab in earlier stages
Patients with chronic obstructive pulmonary disease (COPD) who are in their final years of survival do not get the same benefits from pulmonary rehabilitation (PR) as patients who have more years ...
- RESPIRATORY MEDICINE & AIRWAYS: - EGFR expression increases in response to diesel fume exposure
Part Fibre Toxicol 2008; 5: 8: - Diesel exhaust (DE)-induced bronchial epithelial inflammatory responses are mediated by the epidermal growth factor receptor (EGFR), study findings indicate. Thomas ...
- PEDIATRY : - Breastfeeding has no effect on risk for atopy in later childhood
J Allergy Clin Immunol 2008 : - There is no evidence for either a deleterious effect or a protective effect of breastfeeding on the risk for allergic disease at ages 7-8 years, according to ...
- RESPIRATORY MEDICINE : - Older siblings increase likelihood of respiratory symptoms at age 4 years
Clin Exp Allergy 2008; Advance online publication Children with older siblings are more likely to experience respiratory symptoms compared with children who have no siblings or are the oldest child, ...
- COPD: PATOGENESIS:- Loss of small-airway elasticity contributes to COPD
Eur Respir J 2008; 31: 998-1004 The loss of elastic fibres in small airways may contribute to the development of airflow obstruction in chronic obstructive pulmonary disease (COPD), researchers from ...
- NEUTROPHILIC AIRWAYS INFLAMMATION : -THE PURINES ATP and AMP potential biomarkers for neutrophilic airways inflammation
Eur Respir J 2008; 31: 949-956 The purines adenosine triphosphate (ATP) and adenosine monophosphate (AMP) are biomarkers of neutrophilic airways inflammation, according to US researchers. ...
- RESPIRATORY & BIOCHEMICAL & BIOPHYSICS MEDICINE: Thixotropy (conversion of a gel into a fluid during mixing or shaking) conditioning increases COPD exercise capacity
Respir Med 2008; Advance online publication Thixotropy conditioning increases self-paced walking distance in patients with chronic obstructive pulmonary disease (COPD), particularly those with ...
- RESPIRATORY MEDICINE: Mast-cell-derived TNF pivotal in airway inflammation
Eur Respir J 2008; 31: 773-782 Mast cells and mast cell-derived tumor necrosis factor (TNF) are essential for the development of allergic airway diseases such as asthma, according to the results of a ...
